Neuroimmune interactions have been revealed to be at the centre stage of tissue defence, organ homeostasis, and organismal physiology. Neuronal immune cell subsets shown colocalize in discrete environments, forming neuroimmune units that constitute basis for bidirectional interactions. These multitissue drive coordinated responses local systemic signals, which represents an important challenge ...

The nerve injury, whether it results in tissue loss or not, involves cutting off the nerve, making impossible for two portions to interact and, as a result, impairing functionality. Mesenchymal stem cells are one of best options cell therapy many diseases due their distinct functional properties, such potent differentiation capacity, immunomodulatory capacity and growth support. secretome gener...

OBJETIVO: describir el proceso de la migración neuronal para desarrollo del sistema nervioso y conformación cerebro humano METODO: construcción teórica a partir revisión bibliográfica RESULTADOS: epicentro surge una célula llamada radial glial que sirve como precursora neuronas al mismo tiempo guía hasta las ocupen lugar definitivo dentro nervioso. Como resultado un fallo también se mencionan a...

Neuronal migration is a fundamental process of mammalian brain development. In migrating neurons, the nuclear membrane protein Nesprin-2 has been shown to serve as an adaptor pull nucleus along microtubule tracks. Current evidence that binds both minus-end-directed motor dynein well plus-end-directed kinesin. However, translocation neuronal long thought be primarily driven by motors. Intriguing...

Este trabajo se enmarca en las aplicaciones de redes neuronales el estudio y modelamiento delos fenómenos presentes la fotósfera solar. La investigación propuesta basa modelo redesadversarias generativas haciendo uso módulos inteligencia artificial Pytorch. Se busca entrenaruna red neuronal capaz generar grupos imágenes una alta similitud con entrenamiento,dichas corresponden a magnitudes físic...

Background: B cell CLL/lymphoma 2 protein, bcl-2, is an important anti-apoptotic factor that has been implicated in lithium’s neuroprotective effect. However, most studies have focused on assessing the effects of lithium in neurons, ignoring examination of bcl-2 in astrocytes, which also influence neuronal survival and are affected in bipolar disorder. The aim of this study was to evaluate whet...

Spironolactone has produced beneficial effects in animal models of neurodegenerative disorders. However, the underlying mechanisms of this agent on neurons and glia are mostly unknown. Therefore, we aimed to show the effects of spironolactone and fludrocortisone, a mineralocorticosteroid receptor agonist, on neuronal and glial toxicity induced by N-methyl-D-aspartate (NMDA) activation and chlor...

Introduction: For centuries, cannabinoids are known to be effective in pain relief. Itch is an unpleasant sensation that provokes a desire to scratch. Since itch and pain are two sensations sharing a lot in common, we aimed to investigate whether the cannabinoid agonist WIN 55,212-2 reduces serotonin-induced scratching behavior and also observe whether modulation of nitric oxide (NO) production...