نتایج جستجو برای: neuronal injury

تعداد نتایج: 427898  

Journal: :International Journal of Molecular Sciences 2020

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 1998

Journal: :Experimental neurology 2001
M C Lee Y T Chung J H Lee J J Jung H S Kim S U Kim

This study investigates whether the neurohormone melatonin can prevent the retinal neuronal injury caused by reactive oxygen species (ROS) in cultured human retinal neuronal cells. Cultures of human retinal neuronal cells established from a variety of donors were grown to 14 days and then subjected to experimental hypoxanthine/xanthine oxidase (HX/XO)-induced injury. Intracellular production of...

Journal: :Future neurology 2013
Kellie Park Thomas Biederer

Few specific therapeutic targets exist to manage brain injury, despite the prevalence of stroke or traumatic brain injury. With traumatic brain injury, characteristic neuronal changes include axonal swelling and degeneration, and the loss of synapses, the sites of communication between neurons. This is followed by axonal sprouting and alterations in synaptic markers in recovery. The resulting c...

2012
Zhao Feng Peng Minghui Jessica Chen Jayapal Manikandan Alirio J Melendez Guanghou Shui Françoise Russo-Marie Matthew Whiteman Philip M Beart Philip K Moore Nam Sang Cheung

Nitric oxide is implicated in the pathogenesis of various neuropathologies characterized by oxidative stress. Although nitric oxide has been reported to be involved in the exacerbation of oxidative stress observed in several neuropathologies, existent data fail to provide a holistic description of how nitrergic pathobiology elicits neuronal injury. Here we provide a comprehensive description of...

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