The development of pharmacotherapies for cocaine addiction has been disappointingly slow. However, new neurobiological knowledge of how the brain is changed by chronic pharmacological insult with cocaine is revealing novel targets for drug development. Certain drugs currently being tested in clinical trials tap into the underlying cocaine-induced neuroplasticity, including drugs promoting GABA ...

Neuroplasticity or the brain’s ability to change and reorganize following injury, is a known critical factor to the rehabilitative process following neurological injuries [1]. In addition, neuroplasticity is now being considered as a component that may influence rehabilitation following musculoskeletal injuries [2]. While many non-invasive brain stimulation studies have focused on increasing co...

The primary objective of this review article is to summarize how the neuroscience of brain plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is changing the therapeutic landscape for professional communities addressing brain-based disorders and disease. After considering the neurological bases of training-driven neuroplasticity, we shall describe how th...