background: misoprostol, a prostaglandin e1 analogue compared to prostaglandin e2, has the advantage of being inexpensive and stable at room temperature, with its proven efficacy and safety. however studies on the effect of ph on the efficacy of misoprostol have yielded conflicting results. thus its use in the induction of labour in patients with premature rupture of membrane requires further i...

BACKGROUND The 2014 International Pressure Ulcer Prevention (PUP) Clinical Practice Guidelines (CPG) provides the most current evidence based strategies to prevent Pressure Ulcer (PU). The evidence upon which these guidelines have been developed has predominantly been generated from research conducted in developed countries. Some of these guidelines may not be feasible in developing countries d...

Application of topical medication remains an essential component of clinical physiotherapy practice but previous reports have revealed poor knowledge of medications among Nigerian physiotherapists. Also, there are arrays of topical medications available but there is envelope of doubts on what determines the choice of Nigerian physiotherapists. The primary aims of this study were to investigate ...

Background: Electroconvulsive therapy (ECT) provokes abrupt changes in systemic haemodynamics. We compared the effects of modified (propofol and thiopentone) versus unmodified ECT on haemodynamic responses of patients scheduled for ECT in two Nigerian tertiary hospitals between September 2008 and March 2009.Methods: In a prospective, randomized study, sixty patients slated for ECT were allocate...

BACKGROUND Oral and maxillofacial surgery is still evolving, with the scope of practice in Nigeria inadequately determined. AIMS AND OBJECTIVES This study aims to ascertain the level of practice in various parts of the country vis-a-vis the global trend and factors influencing the scope in Nigeria. DESIGN OF THE STUDY Cross-sectional. SETTING The study was carried out at the University of...

BACKGROUND Psychiatric liaison services are rare in trauma units of various hospitals in Nigeria and other sub-Saharan African countries. The occurrence of road traffic accidents (RTAs) resulting from low standard of road construction and inadequate maintenance have been on the increase in Nigeria. While the physical consequences of such RTAs are obvious, the psychological consequences are ofte...

A case of pyostomatitis vegetans and ulcerative colitis in a 26-year-old African is described. The colitis, confirmed clinically and radiologically, antedated the development of pyostomatitis. Systemic corticosteroids apparently cured the pyostomatitis but only caused an improvement in the ulcerative colitis. The rarity of ulcerative colitis amongst the Nigerian population and of pyostomatitis ...

Sera from 53 Nigerian patients satisfying the American Rheumatism Association criteria for a diagnosis of definite or probable rheumatoid arthritis and sera from sick and healthy Nigerian controls were tested for rheumatoid factor, autoantibodies, and immunoglobulin levels. Rheumatoid factor and autoantibodies were found no more frequently in patients with rheumatoid arthritis than in controls....