Chronic granulomatous disease (CGD) is an inherited disease of the phagocyte NADPH oxidase system that causes defective production of toxic oxygen metabolites, leading to impaired bacterial and fungal killing, and recurrent life threatening infections; mostly by catalase producing organisms. Nocardiosis in CGD is well described, however actinomycosis is rare. We describe a patient of CGD with a...

Nocardiosis is an uncommon infection caused by Nocardia species, a group of aerobic actinomycetes. Disease in humans is rare and often affects patients with underlying immune compromise. Acquisition of this organism is usually via the respiratory tract, but direct inoculation into the skin is possible, usually in the setting of trauma. We report an encounter of a previously healthy man, with ce...

Pulmonary ray fungus is a relatively rare condition. In 1938 Cope4 was able to collect 200 cases of pleuro-pulmonary actinomycosis from the literature and Reiter17 in 1954, noted 47 cases of this disease described during the preceding ten years; of pulmonary nocardiosis only 47 cases have been described.20 It is reported that in large hospitals clinicians encounter three to five cases of pulmon...

Pulmonary nocardiosis is a well-described infection in immunocompromised patients; however, it is less well documented in patients with AIDS. The pulmonary manifestation in 21 HIV-positive patients who developed pulmonary infection with Nocardia asteroides is described. The radiographic picture included lobar or multilobar consolidation (52 percent [11/21]), solitary masses (24 percent [5/21]),...

Se denominan pseudomicosis a las infecciones generadas por microorganismos que parecen hongos pero no lo son. En esta revisión se abordan desde una perspectiva etiológica, epidemiológica y clínica algunas de oportunistas más frecuentes: actinomicosis, botriomicosis, nocardiosis prototecosis. Adicionalmente, revisan herramientas clínicas paraclínicas para facilitar su diagnóstico actualizan paut...

A 72-year-old Japanese woman was admitted at Saga University Hospital for fever, malaise, and productive cough. Six years ago, she had been diagnosed with bronchial asthma and was treated with inhaled corticosteroids. Chest radiograph and computed tomography on admission showed infiltrates in the right middle lobe, a mass lesion in the left lower lobe, and bronchiectasis in both lower lobes. Sp...

Nocardia otitidiscaviarum was seldom reported to cause primary cutaneous nocardiosis, which is difficult to diagnosis due to its nonspecific clinical features. Misdiagnosis of the disease could result in inappropriate treatment and chronic protracted lesions. In this report, we described a previously misdiagnosed case of primary cutaneous nocardiosis caused by N. otitidiscaviarum in a 30-year-o...

We report the case of an 84-year-old male who was admitted to the hospital with persistent cough and dyspnea. An initial chest X-ray revealed pulmonary infiltrates. Nocardia asteroides was detected in sputum, and the patient was treated with antibiotics. However, his symptoms did not completely resolve. He was admitted multiple times, and his symptoms relapsed after every discharge. He was fina...