Thyroid nodules are common. The clinical importance of thyroid nodules is related to excluding malignancy (4.0 to 6.5% of all thyroid nodules), evaluate their functional status and assess for the presence of pressure symptoms. Incidental thyroid nodules are being diagnosed with increasing frequency in the recent years with the use of newer and highly sensitive imaging techniques. The high preva...

Thyroid nodules are clinically palpable in 4-7% of adults in the United States. With ultrasound examination, thyroid nodules are identified in up to 70% of adults. In asymptomatic individuals, the potential for malignancy underlies the clinical importance of investigating thyroid nodules. Increased diagnostic accuracy has improved non-operative management of benign thyroid lesions. Appropriate ...

IMPORTANCE Few studies have evaluated the association of radiation dose with thyroid nodules among adults exposed to radiation in childhood. OBJECTIVE To evaluate radiation dose responses on the prevalence of thyroid nodules in atomic bomb survivors exposed in childhood. DESIGN, SETTING, AND PARTICIPANTS This survey study investigated 3087 Hiroshima and Nagasaki atomic bomb survivors who we...

PURPOSE To evaluate thin-section computed tomographic (CT) characteristics of malignant nodules on the basis of overall appearance (pure ground-glass opacity [GGO], mixed GGO, or solid opacity) in comparison with the appearance of benign nodules. MATERIALS AND METHODS Institutional review board approval and patient consent were obtained. Follow-up diagnostic CT was performed in 747 suspicious...

BACKGROUND/AIM The major one among the procedures for evaluating changes in the thyroid nodules is fine needle aspiration biopsy (FNAB). Thyroid scintigraphy is commonly used in diagnostic algorithm of nodules. Less than 5% of examined nodules show to be malignant. Scintigraphically, nodules could be classified as functional and nonfunctional. It is estimated that the risk of malignancy in nonf...

BACKGROUND Surgical resection of small pulmonary nodule is challenging via thoracoscopic procedure. We describe our experience of computed tomography (CT)-guided needle puncture localization of indeterminate pulmonary nodules prior to video-assisted thoracoscopic surgery (VATS). METHODS From January 2011 to July 2014, 78 consecutive patients underwent CT-guided marking for the localization of...

Objective. Ultrasonographic characteristics are associated with thyroid malignancy. Our aim was to compare the diagnostic value of ultrasound features in the detection of thyroid malignancy in both solid and mixed nodules. Methods. We prospectively studied female patients (≥50 years) referred to ultrasound-guided fine needle aspiration biopsy. Ultrasound features considered suspicious were hypo...

INTRODUCTION Adenocarcinomas, commonly present as a dominant lesion (DL) with additional nodules in the ipsilateral or contralateral lung. We sought to determine the fate and management of the secondary nodules and to assess the risk of these nodules using the Lung CT Screening Reporting and Data System (Lung-RADS) criteria and the National Comprehensive Cancer Network (NCCN) Guidelines to dete...

With increased health screening and the development of highresolution ultrasound (US) techniques, thyroid nodules are commonly seen in clinical practice. When a patient presents with a thyroid nodule, the primary concern is whether it is benign or malignant. After ruling out malignancy with fine needle aspiration (FNA), which is typically performed with ultrasonographic guidance, the next conce...

The sequence of possible cellular, tissue, biochemical, and molecular changes that are important during the development of experimental liver cancer with chemicals is reviewed from the viewpoint of the author's experience in carcinogenesis over the past 25 years. The development of a new model for the analysis of liver carcinogenesis, the resistant hepatocyte model, is briefly described, as are...