Continental freshwater systems have now been shown to be globally significant sources of methane, but there are still large uncertainties associated with freshwater methane fluxes. Studies to date have mainly focused on either ebullition of bubbles originating from sediments or on diffusive fluxes of dissolved methane across the air–water interface. We examined the potential influence of a new ...

The moisture diffusion behaviors of 3D woven composites exhibit non-Fickian properties when they are exposed to a hydrothermal environment. Although some experimental works have been undertaken investigate this phenomenon, very few mathematical on predictions available in the literature. To capture behavior composites, study first utilized time fractional equation derive percentage content homo...

Metoprolol succinate (MS) gastroretentive (GR) controlled release system was formulated to increase gastric residence time leading to improved drug bioavailability. Box-Behnken model was followed using novel combinations of sodium alginate (SA), sodium carboxymethylcellulose (NaCMC), magnesium alumino metasilicate (MAS) as independent variables. Floating lag time (Flag), t25, t50, t75, diffusio...

Purpose of present study was to develop eight formulations chlorpheniramine (CPM) niosomes according 23 factorial design, characterise on the basis various evaluation tests, i.e. in vitro drug release, SEM, FTIR, TGA and release kinetics, optimise formulation data, formulate gel optimised dispersion, perform vivo histopathological using dispersion rabbits. Here, N3 having low level cholesterol ...

Introduction: The current work was aimed to design and synthesize novel crosslinked pH-sensitive gelatin/pectin (Ge/Pec) hydrogels using different polymeric ratios and to explore the effect of polymers and degree of crosslinking on dynamic, equilibrium swelling and in vitro release behavior of the model drug (Mannitol). Methods: The Ge/Pec based hydrogels were prepared using glutaraldehyde as t...

Solubility and diffusivity of Thyme, Cinnamon Oregano essential oils in nanocellulose films, with different carboxymethylation degree, were investigated view potential use active packaging applications. liquid resulted to increase the degree for both, Thyme while it was non-monotonous Cinnamon. showed higher solubility (about 20%wt) followed by Oregano. The sorption kinetics substantially Ficki...

Hybrid polymeric networks composed of polyacrylamide and chitosan were developed to determine their swelling and ascorbic acid delivery kinetics at various chitosan concentrations. The hybrid acrylamide/chitosan hydrogels were synthesized in aqueous itaconic acid solution (1% w/w). Young’s modulus was also evaluated for the hydrogels, and the results were correlated with the swelling properties...

OBJECTIVE The objective of the research was to formulate and evaluate sumatriptan succinate-loaded chitosan nanoparticles for migraine therapy in order to improve its therapeutic effect and reduce dosing frequency. MATERIAL AND METHODS The Taguchi method design of experiments (L9 orthogonal array) was applied to obtain the optimized formulation. The sumatriptan succinate-loaded chitosan nanop...

A thermokinetic model of hydrogen diffusion across a metallic tube is established. It includes the enthalpy change of the metal– hydrogen reaction, heat losses, dependences of reaction rate and hydrogen diffusion coefficient on temperature, and self-stress effects, etc. A phenomenon, the super fast diffusion of hydrogen before the up-hill diffusion and Fickian diffusion during hydrogen gas char...

We present an exact expression for the upscaled dynamic dispersion coefficient (D) for one-dimensional transport by Hagen-Poiseuille flow which is the basis for modeling transport in porous media idealized as capillary tubes. The theoretical model is validated by comparing the breakthrough curves (BTCs) from a 1D advection-dispersion model with dynamic D to that from direct numerical solutions ...