OBJECTIVES This study was designed to compare different proposed methods of assessing adherence with angiotensin-converting enzyme (ACE) inhibitor (ACEI) therapy in chronic heart failure. BACKGROUND The use of ACEIs in chronic heart failure gives us a unique opportunity to assess a patient's adherence by measuring whether the expected biochemical effect of an ACEI is present in the patient's ...

Medication nonadherence is a public health epidemic. Numerous studies evaluating a wide variety of drugs and conducted in varied healthcare settings have described the consistent nature of this problem.1 Hypertension is no exception: Almost half of patients become nonadherent to their antihypertensive medication within 1 year of initiating therapy.2 Although difficult to quantify precisely,3 th...

IMPORTANCE Understanding factors that lead to nonadherence to glaucoma treatment is important to diminish glaucoma-related disability. OBJECTIVES To determine whether the implementation of the Medicare Part D prescription drug benefit affected rates of cost-related nonadherence and cost-reduction strategies in Medicare beneficiaries with and without glaucoma and to evaluate associated risk fa...

LEARNING OBJECTIVES Upon completion of this activity, participants will be able to: 1. Identify barriers to medication adherence among their patients. 2. Take steps to reduce nonadherence among glaucoma patients. 3. Identify glaucoma patients who may benefi t from sustained-release therapies by increasing awareness of nonadherence with eye drop treatment. 4. Compare diff erent drug-delivery sys...

Approximately 50-75% of all patients do not take their antipsychotic medication as prescribed. The current study examined reasons why patients continue versus discontinue antipsychotic medication. We were particularly interested to which extent positive attitudes towards psychotic symptoms foster medication nonadherence. An anonymous online questionnaire was set up to decrease response biases. ...

Copyright: © Cross RK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Inflammatory bowel disease (IBD), comprised of Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory condition of th...

The effectiveness of any treatment depends on three principal factors: efficacy, adverse effects, and adherence. The first two factors (efficacy and adverse effects) have been the focus of medical reasoning for decades. Adherence has been recently receiving increased attention in the pharmacological treatment of medical conditions such as diabetes and hypertension, as well as psychiatric disord...

BACKGROUND There was limited published data on target organ damage (TOD) and the effect of nonadherence to practice guidelines in Ethiopia. This study determined TOD and the long term effect of nonadherence to clinical guidelines on hypertensive patients. METHODS An open level retrospective cohort study has been employed at cardiac clinic of Gondar university hospital for a mean follow-up per...

Despite advances in treatments for cardiovascular risk factors, such as hypertension, poorly controlled blood pressure (BP) continues to be a significant public health problem in the United States. Medication nonadherence is a pervasive problem contributing to inadequate BP control. The patient–provider relationship offers an ideal opportunity to address patient nonadherence because providers’ ...

OBJECTIVE The aim of this study was to determine the rate of missed treatments among hemodialysis (HD) patients, and the association between treatment nonadherence and clinical outcomes. DATA SOURCE The data used in this study were based on electronic medical records and Medicare claims. STUDY DESIGN This is a retrospective, observational study. PRINCIPAL FINDINGS HD patients miss 9.9% of...