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Drug-induced liver injury (DILI) is an important cause of mortality and morbidity in the general population. Patients suffering from DILI may present with symptoms ranging from minor, nonspecific changes in hepatic structure and function to fulminant hepatic failure or chronic hepatitis. Thiocolchicoside is widely used as a muscle relaxant. The primary side effects of thiocolchicoside are nause...
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Effect of L-5-HTP (L-5-hydroxytryptophane) on the release of human growth hormone (HGH), thyroid stimulating hormone (TSH) and immunoreactive insulin (IRI) was investigated in 7 normal subjects and 25 patients with endocrine disorders. A single oral dose of 200mg of L-5-HTP showed the elevation of HGH in plasma; however, no release of TSH and insulin in plasma of normal subjects. HGH response t...
The pituitary-Thyroid axis of 12 Acromegalic patients was evaluated by measurement of the concentration (Total and free of thyroxine T4, T3 and revers T3 (rT3) and TSH, GH and prolactin before and after in stimulation with TRH. Using an ultrasensitive method of TSH measurement (IRMA) basal serum TSH levels of patients (0.76, 0.07-l.90mlU/L) were found slightly but significantly (P < 0.01), low...
117 postmenopausal women were divided into Normal, Bone loss (BL), and Osteoporosis group. Compared with Normal group (120.96 ± 43.18 μg/L), the serum ferritin (Fer) in BL (223.37 ± 130.27 μg/L) and Osteoporosis group (307.50 ± 161.48 μg/L) was significantly increased (p < 0.05). Fer level was negatively correlated with BMD (p < 0.01). TRACP levels in Osteoporosis group (4.37 ± 1.69 U/L) were s...
SUMMARY In 28 school children with primary hypothyroidism due to iodine deficiency, 100 µg levothyroxine (L-T4} was administered for nine weeks and resulted in normalization of serum T4, T3, and TSH. Five months after withdrawal of L-T 4 , thyroid function was normal in the majority of subjects. Serum T4 was 8.6±2.3 µg/dl ; T3, 156±2.3 ng/dl; and TSH, 6.9± 12.7 µU/ml. Only one subjects showed ...
Histologically confirmed small cell lung cancer associated with Cushing's syndrome and elevated amylase is rarely described in the literature. We present a case of a 63-year-old patient admitted to cardiology department due to shortness of breath, exhaustion, palpitations and nausea. Elevated values of troponin and electrocardiography suggested that he could have acute coronary syndrome. Accord...
Pancreatitis in children is inflammation of the pan-creas gland which presents with epigastric abdominal pain and elevated levels of digestive enzymes, and it is an important cause of mortality and morbidity [1]. Although hyperamylasemia and hyperlipasemia are relatively frequently seen in gastroenteritis, pancreatitis is very uncommon [2]. Rotavirus infection and pancreatitis together are seen...
A 75-year-old woman who had had cutaneous lupus erythematosus for 18 months was initially treated with hydroxychloroquine. This treatment was stopped after 4 weeks because of nausea. She was then treated successfully with oral corticosteroids for 3 months and the steroid therapy could be discontinued. Her skin lesions relapsed some 5 months later and she was given dapsone 100 mg/day. Within 10 ...
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