mohammad reza heydari department of pharmacology, medical school, shiraz university of medical sciences, shiraz, iran majid fardaei department of medical genetic, medical school, shiraz university of medical sciences, shiraz, iran; department of medical genetic, medical school, shiraz university of medical sciences, zand street, postal code: 71348-53185, shiraz, iran. tel: +98-7132349610, fax: +98-7132349610 mohammad rahim kadivar department of pediatric, namazi hospital, shiraz university of medical sciences, shiraz, iran abbas rezaianzadeh department of epidemiology, shiraz university of medical sciences, shiraz, iran mohammad reza panjehshahin department of pharmacology, medical school, shiraz university of medical sciences, shiraz, iran zeinab gholami bardeji department of radiology, medical imaging research center, namazi hospital, shiraz university of medical sciences, shiraz, iran