INTRODUCTION Olfaction is frequently affected in chronic rhino-sinusitis with polyposis and has been recognised to have important impact on quality of life. Surgical resolution on cases of maximal medical therapy failure is an option to relieve symptoms, with debates as to how extensive surgery should be. A more radical approach will achieve better disease control with less relapse, but can als...

Isocyanate is the most prevalent agent in occupational asthma(OA) in Korea. We analyzed 43 toluene diisocyanate(TDI) induced OA patients of whom 81% were found to be spray painters. The bronchial sensitivity of all subjects was confirmed by TDI-bronchial challenge test. Serum-specific IgE antibodies to isocyanate-human serum albumin(HSA) conjugate were detected by RAST technique(Pharmacia, Swed...

Staphylococcus spp. are a challenge for the modern day medicine due to the complexity of disease process and presence and expression patterns of their respective virulence factors. The members of this genus possess many known toxins, multiple immunoavoidance mechanisms and adherence factors, most of which demonstrate transient, timed, and diseasespecific expression. They cause different types o...

Silent sinus syndrome (SSS) or chronic maxillary atelectasis (CMA) is characterized by enophthalmos or hypo Globus along with maxillary sinus atelectasis and lateralization of the uncinate process without classic rhino sinusitis symptoms. A previous description of surgical management includes maxillary antrostomy with orbital floor repair via an implant, possibly as a two-stage procedure. The o...

Rhino-orbito-cerebral mucormycosis is a rare life-threatening opportunistic fungal infection caused by fungi from the order Mucorales [1]. The disease commonly affects immunocompromised patients, especially ketoacidotic diabetic patients [2]. We report a case of Rhinocerebral mucormycosis in a 48-year-old diabetic patient, who presented to our department with the complaints of exophthalmos in t...

Primary ciliary dyskinesia (PCD) is characterised by chronic suppurative lung disease, rhino-sinusitis, hearing impairment and sub-fertility. We have developed the first multidimensional measure to assess health-related quality of life (HRQoL) in adults with PCD (QOL-PCD).Following a literature review and expert panel meeting, open-ended interviews with patients investigated the impact of PCD o...

Introduction. The contribution of tracheotomy in comparison to intubation in patients on the resuscitation ward is debated. The main purpose of our study is to assess if tracheotomy compared to prolonged intubation, reduces the whole duration of ventilation, the frequency of nosocomial pneumopathy, the mean duration of hospitalisation in the resuscitation ward and mortality. Patients and method...