Abstract The World Health Organization (WHO, 2019) reports that schizophrenia affects approximately 20 million people worldwide, and the annual number of new cases is estimated at 1.5%/10,000 people. As a result, there demand for making relevant medicines work better. Using fluphenazine (FZN) drug delivery system has been optimized using nanoparticles (NPs) technology an important alternative t...

Traffic Engineering (TE) approaches are increasingly important in network management to allow an optimized configuration and resource allocation. In link-state routing, the task of setting appropriate weights to the links is both an important and a challenging optimization task. A number of different approaches has been put forward towards this aim, including the successful use of Evolutionary ...

Problems that are not aligned with the coordinate system can present difficulties to many 15 optimization algorithms, including evolutionary algorithms, by trapping the search on a ridge. The ridge problem in single-objective optimization is understood, but until now 17 little work has been done on understanding this issue in themulti-objective domain.Multiobjective problemswithparameter intera...

The time-cost trade-off problem is a known bi-objective problem in the field of project management. Recently, a new parameter, the quality of the project has been added to previously considered time and cost parameters. The main specification of the time-cost trade-off problem is discretization of the decision space to limited and accountable decision variables. In this situation the efficiency...

The nature of optimization for intermittent sugar cane crystallization process is to obtain ideal crystals. One typical difficulty in crystallization optimization refers to the simultaneous effects of both seeding characters and process variables on the final crystal size distribution (CSD) parameters, including mean size (MA) and coefficient of variation (CV). And the application of traditiona...

The content ranking problem in a social news website, is typically a function that maximizes a scalar metric of interest like dwell-time. However, like in most real-world applications we are interested in more than one metric—for instance simultaneously maximizing click-through rate, monetization metrics, dwell-time— and also satisfy the traffic requirements promised to different publishers. Al...

In Digital Signal processing domain the Quadrature Mirror Filter (QMF) design problem is one of the most important problems of current interest. While designing a Quadrature Mirror Filter the goal of the designer is to achieve minimum values of Mean Square Error in Pass Band (MSEP), Mean Square Error in Stop Band (MSES), Square error of the overall transfer function of the QMF bank at the quadr...

With the development of customization concept, small-batch and multi-variety production will become one major modes, especially for fast-moving consumer goods. However, this mode has two issues: high cost long manufacturing period. To address these issues, study proposes a multi-objective optimization model flexible flow-shop to optimize scheduling, which would maximize efficiency by minimizing...