Neurotensin (NT) is a neuropeptide identical in mice and humans that is produced and released in many CNS regions associated with maternal behavior. NT has been linked to aspects of maternal care and previous studies have indirectly suggested that endogenous NT signaling is altered in the postpartum period. In the present study, we directly examine whether NT and its receptors exhibit altered g...

More and more high available applications are implemented on Windows NT. However, the current version of Windows NT (NT4) does not provide some facilities that are needed to implement these fault tolerant applications. In this paper, we describe a set of components collectively named NT-SwiFT (Software Implemented Fault Tolerance) which facilitates building fault-tolerant and highly available a...

Résumé. Suite à la survenue récente de scandales financiers, la synthèse des idées mobilisables en gouvernance d’entreprise semble désormais essentielle si l’on veut sécuriser les investisseurs. Dans cette perspective, le présent projet de recherche consiste à mettre en œuvre un panel d’outils d’analyse de données textuelles (Alceste, Syntex, Tropes-Zoom/Decision Explorer, Wordmapper, Weblex) a...

NT offers a wealth of measurement data regarding system, interface and application performance. In fact, there is so much information that the greatest danger may well be data overload. This presentation will offer a set of key metrics that will quickly supply an overview of system performance to the analyst. These can be used to quickly assess the status of an NT system, identify bottlenecks a...

The neuropeptide neurotensin (NT) elicits hypothermic and naloxone-insensitive analgesic responses after brain injection. Recent pharmacological evidence obtained with NT agonists and antagonists suggests that these effects are mediated by a receptor distinct from the initially cloned high-affinity NT receptor (NTR1). The recent cloning of a second NT receptor (NTR2) prompted us to evaluate its...

Prostate cancer PC3 cells expressed constitutive protein kinase C (PKC) activity that under basal conditions suppressed neurotensin (NT) receptor function. The endogenous PKC activity, assessed using a cell-based PKC substrate phosphorylation assay, was diminished by PKC inhibitors and enhanced by phorbol myristic acid (PMA). Accordingly, PKC inhibitors (staurosporine, Go-6976, Go-6983, Ro-3182...

BACKGROUND Chinese herbal extract Number Ten (NT) is a dietary herbal formulation prepared from rhubarb, ginger, astragalus, red sage and tumeric. This study tested the effectiveness of NT in reducing body weight gain in rats. METHODS Sixty female Wistar rats were fed a high fat diet and acclimated to gavage feeding. The rats were divided into five treatment groups: (1) Control (n = 15); (2) ...