This is a review of research aimed at elucidating how various opiate analgesia substrates in rat brain stem interact with one another to bring about opiate analgesia. The three substrates studied are the midbrain periaqueductal grey (PAG), the bulbar nucleus raphe magnus (RM), and the bulbar nucleus reticularis paragigantocellularis (PGC). The methods used in the reviewed studies are unique in ...

In order to get a more complete picture of how labor supply is affected by economic incentives, the effects on absenteeism and not just on contracted hours should be taken into account. In particular, absenteeism due to sick leave can be considerable. In this paper we examine whether the level of sick leave compensation affects sick leave behavior. Using time-series data for Sweden spanning a l...

In rats, opioids produce analgesia in large part by their effects on two cell populations in the medullary raphe magnus (RM). To extend our mechanistic understanding of opioid analgesia to the genetically tractable mouse, we characterized behavioral reactions and RM neural responses to opioid administration. d-Ala(2), N-Me-Phe(4)-Gly(5)ol-enkephalin, a mu-opioid receptor agonist, microinjected ...

Neurons in the medullary raphe magnus (RM) that are important in the descending modulation of nociceptive transmission are classified by their response to noxious tail heat as ON, OFF, or NEUTRAL cells. Experiments in anesthetized animals demonstrate that RM ON cells facilitate and OFF cells inhibit nociceptive transmission. Yet little is known of the physiology of these cells in the unanesthet...

Retailing Innovations in a Globalizing Retail Market Environment Werner Reinartz a,∗, Benedict Dellaert b,1, Manfred Krafft c,2, V. Kumar d,3, Rajan Varadarajan e,4 a Department of Retailing and Customer Management, University of Cologne, Albertus-Magnus-Platz 1, 50923 Cologne, Germany b Department of Business Economics, Erasmus University Rotterdam, Postbus 1738, 3000 DR, Rotterdam, The Nether...

A great deal of late bidding has been observed on internet auctions such as eBay, which employ a second price auction with a fixed deadline. Much less late bidding has been observed on internet auctions such as those run by Amazon, which employ similar auction rules, but use an ending rule that automatically extends the auction if necessary after the scheduled close until ten minutes have passe...

The small 62-residue IgG-binding domain B1 of protein L from Peptostreptococcus magnus (Ppl-B1) has proven to be a simple system for the study of the thermodynamics and kinetics of protein folding. X-ray diffraction studies have been initiated in order to determine how the thermostability, folding and unfolding rates of a series of point mutations spanning Ppl-B1 correlate with the high-resolut...

Arsenic is the chemical element that has the symbol As, atomic number 33 and atomic mass 74.92. Arsenic was first documented by Albertus Magnus in 1250.[4] Arsenic is a notoriously poisonous metalloid with many allotropic forms, including a yellow (molecular non-metallic) and several black and grey forms (metalloids). Three metalloidal forms of arsenic, each with a different crystal structure, ...

K e y w o r d s : Bombus lucorum-complex, Bombus cryptarum, Bombus magnus, cryptic species, morphological characters, future issues

We report a case of Finegoldia magna (formerly known as Peptostreptococcus magnus) mediastinitis following coronary artery bypass in a 50-year-old patient. Even if staphylococci remain the main causative organism of postoperative mediastinitis, the responsibility of anaerobic bacteria must be considered in cases of fever and sternal drainage with negative blood cultures.