Therapeutic repair of myelin disorders may be limited by the relatively slow rate of human oligodendrocyte differentiation. To identify appropriate pharmacological targets with which to accelerate differentiation of human oligodendrocyte progenitors (hOPCs) directly, we used CD140a/O4-based FACS of human forebrain and microarray to hOPC-specific receptors. Among these, we identified CHRM3, a M3...

Three strains of Escherichia coli isolated from infectious processes in a calf, a dog, and a cat were examined for their capacity to produce disease or death, or both, in newborn gnotobiotic piglets. The O groups represented by these particular strains of E. coli were O4: (canine origin), O6: (feline origin), and O39: (bovine origin). All three isolates upon oral administration proved to be pat...

The compound LLPNP crystallizes in orthorhombic system, P21 21 21 space group with four molecules in the asymmetric unit. The crystal data for LLPNP is tabled. The lysine molecule (C1-C6/N1/N2/O1/O2) is protonated while the paranitrophenol molecule is deprotonated (C7-C12/N3/O3/O4/O5). The paranitrophenol moiety makes a dihedral angle of 85.87 (9)° with the lysine moiety which shows that they a...

Coal ash is one of the significant factors for operating efficiency pressurized coal chemical looping gasification (CLG). To explore influence mechanism physical deposition and combination on iron-based oxygen carrier (OC) under conditions, effects content, components pressure reduction performance Fe2O3/Al2O3 OC are investigated. The micro-structure phase transformation particles conditions ch...

Polyaniline/Fe3 O4 magnetic nanoparticles were synthesized and employed as a sorbent for the magnetic solid phase extraction (MSPE) of seven triazine herbicides from environmental water samples. The properties of the prepared magnetic sorbent were characterized using field emission-scanning electron microscopy (FE-SEM), fourier transform infrared spectroscopy (FT-IR), vibrating sample magnetome...

Serum-free mouse embryo (SFME) cells, the astrocyte progenitor cells in the central nervous system (CNS), were exposed to 10 ng/ml leukemia inhibitory factor (LIF) and 10 ng/ml bone morphogenic protein 2 (BMP2) to induce differentiation, and expression of cell-type specific markers. Nestin, a marker of early neural lineage, betaIII-tubulin, a marker of neuronal lineage, oligodendrocyte marker O...

Targeted improvement of the low efficiency of water oxidation during the oxygen evolution reaction (OER) is severely hindered by insufficient knowledge of the electrocatalytic mechanism on heterogeneous surfaces. We chose LiMn2 O4 as a model system for mechanistic investigations as it shares the cubane structure with the active site of photosystem II and the valence of Mn3.5+ with the dark-stab...

Nitrosylation of the chelate-thiolate-containing dinitrosyliron complex (DNIC) [(S(CH(2))(3)S)Fe(NO)(2)](-) triggers nitric oxide (NO) activation to generate the homoleptic nitrosyl {Fe(NO)(2)}(9) DNIC [Fe(NO)(4)](-) (1) made up of two nitroxyls (or two NO anions) attached to a delocalized {Fe(NO)(2)}(9) motif. The significantly longer N3-O3/N4-O4 [1.380(12) and 1.280(12) Å] and Fe1-N3/Fe1-N4 [...