نتایج جستجو برای: octreotate

تعداد نتایج: 223  

Objective(s):Lutetium-177 can be made with high specific activity and with no other isotopes of lutetium present, referred to as “No Carrier Added” (NCA) 177Lu. We have radiolabelled DOTA-conjugated peptide DOTA‐(Tyr3)‐octreotate with NCA 177Lu (“NCA-LuTATE”) and used it in nearly 40 therapeutic administrations for subjects with neuroendocrine tumours or meningiomas. In this paper, we report on...

2012
Michael C Kreissl Heribert Hänscheid Mario Löhr Frederik A Verburg Markus Schiller Michael Lassmann Christoph Reiners Samuel S Samnick Andreas K Buck Michael Flentje Reinhart A Sweeney

BACKGROUND External beam radiotherapy (EBRT) is the treatment of choice for irresectable meningioma. Due to the strong expression of somatostatin receptors, peptide receptor radionuclide therapy (PRRT) has been used in advanced cases. We assessed the feasibility and tolerability of a combination of both treatment modalities in advanced symptomatic meningioma. METHODS 10 patients with irresect...

Journal: :Pharmaceuticals 2023

Peptide receptor radionuclide therapy (PRRT) has been applied to the treatment of neuroendocrine tumors (NETs) for over two decades. However, improvement is still needed, and targeted alpha (TAT) with emitters such as lead-212 (212Pb) represents a promising avenue. A series ligands based on octreotate was developed. Lead-203 used an imaging surrogate selection best candidate studies lead-212. 2...

Journal: :AACE clinical case reports 2023

Background/ObjectiveTo report a dramatic and immediate clinical biochemical response during treatment with octreotide in patient functioning mesenteric paraganglioma (PGL).Case ReportA 44-year-old woman was admitted severe hypertensive crisis blood pressure reaching 260/150 mm Hg. She 2 months postpartum had been previously diagnosed pre-eclampsia. Secondary hypertension suspected. This confirm...

Journal: : 2022

Abstract
 Objective: 
 Somatostatin analogs (SSA) are used in treating low-grade neuroendocrine tumors, mainly because of their antiproliferative effect. 68Ga tetraazacyclododecantetraacetic acid-DPhe1-Tyr3-octreotate (DOTATATE) PET/CT as somatostatin receptor imaging has been widely recent years. However, there conflicting publications the literature, although guidelines for disconti...

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