Scleral and corneal membranes represent substantial barriers against drug delivery to the eye. Conventional hypodermic needles-based intraocular injections are clinically employed overcome these barriers. This study, for first time, investigated a non-invasive alternative by laser irradiation of ocular tissues. The P.L.E.A.S.E.® device was applied on excised porcine scleral tissues, which showe...

The bibliometric data were extracted from the Scopus database to investigate conceptual framework of ocular nanoemulsion and/or in-situ gel drug delivery system using “ocular” AND “nanoemulsion” OR “in-situ gel” keywords. evaluated with RStudio and VOSviewer program. results reveal that publication trends tend increase continually. India is most impactful country, constructive institution Depar...

The human eye and tear provide essential physiological information for the detection of ocular dysfunctions therapy monitoring. measurements biomarkers in composition are critical disease diagnosis early interventions. Hence, significant efforts dedicated to development functional contact lenses that can quantify analytes condition. combination microfluidics lens technologies offer real-time mo...