Introduction. The major medical concern with giant congenital melanocytic nevi CMN is high risk of developing cutaneous melanoma, leptomeningeal melanoma, and neurocutaneous melanocytosis. Case Report. A 30-year-old woman with a giant congenital melanocytic nevus covering nearly the entire right thoracodorsal region and multiple disseminated melanocytic nevi presented with neurological symptoms...

DEAR EDITOR, A 23-month-old female presented with abnormal cutaneous pigmentation since birth. She had a past history of mediastinal non-Hodgkin lymphoma diagnosed at 9 months of age and treated with surgery and chemotherapy. Family history revealed her grandfathers were brothers, and both died of colon cancer in their fifth decade. Her parents were both fit and well in their early 30s. The pat...

Melasma is a common disorder in women of reproductive age with darker skin tones, but may also affect adolescents, older women on certain medications, and sometimes men. It usually appears as hyperpigmented macules and patches distributed symmetrically on the face, neck and rarely the upper limbs. Although its pathogenesis remains unclear, known risk factors include ultraviolet (UV) radiation, ...