A. KERR GRANT, T. M. ALDOR, E. CURTIN, W. K. NOLAN The Lopresti fiberoptic oesophagoscope was described. The advantages of the instrument were its relative comfort to the patient, the ease of passage, the excellent magnified image of the oesophagus, and the avoidance of a general anaesthetic. Early experience and diagnosis had proved successful in the demonstration of oesophagitis, carcinoma, s...

We present an 82-year-old woman with a 3-month history of progressive dysphagia and a normal initial upper gastrointestinal endoscopy. The diagnosis of pseudoachalasia was suspected by oesophageal manometric and barium swallow studies, and confirmed by biopsies revealing an intestinal type carcinoma of the stomach at a repeated endoscopy. In view of the history of heart disease, diabetes, and o...

The modifying effects of flavonoids diosmin and hesperidin during the initiation and post-initiation phases of oesophageal carcinogenesis initiated with N-methyl-N-amylnitrosamine (MNAN) were investigated in male Wistar rats. At 7 weeks of age, all animals except those treated each test chemical alone and control groups were given weekly intraperitoneal injections of MNAN (12.5 mg/kg body weigh...

perative chemotherapy or neoadjuvant radiochemotherapy, which are associated with a distinct increase of definitive cure rates. In addition, surgical resection was effectively improved in terms of complication rates and postoperative mobilisation by the introduction of minimally invasive laparoscopic as well as thoracoscopic techniques. If centralisation of oesophagectomy in other countries wer...

3 lIson DH. New developments in the treatment of oesophageal cancer. Curr Oncol Rep 2002;4:213-21. 4 Entwistle JW 3rd, Goldberg M. Multimodality therapy for resectable cancer of the thoracic esophagus. Ann Thorae Surg 2002;73:1009-15. 5 Kelsen DP, Ginsberg R, Pajakj TF, Sheahan DG, Gunderson L, Mortimer J, et al. Chemotherapy followed by surgery compared with surgery alone for localized oesopha...

Abstract Objectives SET Domain Containing Protein 8 (SET8), a member of the domain containing methyltransferase family involved in several biological processes and SET8 expression levels, reportedly affects outcomes patients with breast cancer, renal prostate carcinoma, oesophageal squamous cell carcinoma. However, there have been no relevant studies on biofunction use prediction laryngeal carc...

Expanding metal oesophageal stents are being used more commonly to palliate patients with inoperable oesophageal carcinoma. Many reports have so far documented their clinical effectiveness, however, their high acquisition cost has caused on-going concern when compared with the cost of conventional therapies. We reviewed 64 consecutive patients with inoperable oesophageal carcinoma, half of whom...