The oestrogenic activity of human colostrum (Lacassagne & Nyka, 1934) and the undoubted importance of colostrum for the neo-natal calf led us to test bovine colostrum for oestrogenic activity. Oestrogens found in animal tissues and body fluids during the past 23 years, in particular those in pregnant-cow bile (Pearlman, Rakoff, Cantarow & Paschkis, 1947), have always been phenolic in chemical n...