To explore the pathogenesis of nontransfusional iron overload in iron-loading anemia, we examined features of external iron exchange. internal iron kinetics. and tissue iron burden in adult mice with inherited gene-deletion 9-thalassemia. Mice homozygous for $-thalassemia display moderate anemia, reticulocytosis. and shortened red cell survival. whereas heterozygous carriers appear hematologica...

Human and rabbit red blood cells, separated into "young" and "old" age groups by differential flotation on phthalate esters, were fixed with glutaraldehyde and labeled with colloidal ferric oxide. Electron micrographs of thin sections of young cells showed a uniform and dense depostion of positive iron particles. Old cells showed particles deposited irregularly, leaving unlabeled gaps on the me...

Theoretical review of ‘mining pit lakes’ indicates that like natural lakes such lakes display a huge diversity. They are typically in a non-equilibrium state with respect to their surroundings. Hence, at the decommissioning phase of mining operation a detailed technical study are required on different aspects of such created water bodies considering its morphometry, geology, hydrology, water qu...

Iron is necessary for life but also a potent pro-oxidant implicated in the pathogenesis of age-related diseases. We sought to determine if iron levels change with age and by sex in various tissues from several commonly studied mouse strains. Brain, liver, heart, retina, and retinal pigment epithelium (RPE)/choroid were dissected from male and female mice of young adult (2-6 month old) and aged ...

LKAB’s Kiruna Mine, located in northern Sweden, produces about 24 million tons of iron ore yearly using an underground mining method known as sublevel caving. To efficiently run the mills that process the iron ore, the mine must deliver planned quantities of three ore types. We used mixed-integer programming to schedule Kiruna’s operations, specifically, which production blocks to mine and when...

absence of nutritional knowledge is one of the most important reasons of nutritional deficiencies. the aim of this study was to evaluate knowledge, attitude and practices of women about iron deficiency anemia in yazd and orumiyeh. this cross-sectional study was performed on 298 and 242, 15-49 year- old women in yazd and orumiyeh, respectively. questionnaires were prepared to collect the partici...

Rhodomicrobium sp. strain R_RK_3 is an iron-depositing bacterium from which we report the draft genome. This strain was isolated from ochrous depositions of a mining well pump in Germany. The Illumina NextSeq technique was used to sequence the genome of the strain.

Mineral processing and metallurgy production centers may leave a far-reaching fingerprint of soil contamination. This scenario is particularly relevant in the mining district Linares (Southern Spain), where former industrial sites are now dedicated to other land uses. Within this context, we selected five sectors concern region, which currently used as agricultural residential areas. The study ...

Cast iron is a very common and useful metal alloy, characterized by its high carbon content (>4%) in the allotropic state of graphite. The correct shape distribution graphite are essential for ensuring that material has right properties. present investigation examines metallurgical mechanical characterization spheroidal (nodular) cast iron, an alloy derives name excellent properties from pre...

BACKGROUND The serum transferrin receptor (TfR) concentration in adults is suggested to provide a sensitive measure of iron depletion and together with the serum ferritin concentration to indicate the entire range of iron status, from iron deficiency to iron overload. However, little is known about TfR concentrations in children. OBJECTIVE Our objective was to compare serum TfR and ferritin c...