Pulmonary O2 uptake (VO2p) and muscle deoxygenation kinetics were examined during moderate-intensity cycling (80% lactate threshold) without warm-up and after heavy-intensity warm-up exercise in young (n = 6; 25 +/- 3 yr) and older (n = 5; 68 +/- 3 yr) adults. We hypothesized that heavy warm-up would speed VO2p kinetics in older adults consequent to an improved intramuscular oxygenation. Subjec...

This study utilized an experimental format to examine the influence of age designations upon differential ratings of a stimulus person. Two experiments were conducted—one in a college-age population (N = 280); the other in a grouping of older, retired adults (N = 96). In both settings, subjects heard a recorded discussion by a SP described as being either 25 or 65 years of age. Ratings were mad...

BACKGROUND In healthy, normotensive individuals, age-related changes in carotid augmentation index (AI) are more prominent in younger individuals (< 50 years), whereas changes in aortic pulse wave velocity (PWV) are more marked in older individuals (> 50 years). We investigated whether the differential effects of age on AI and PWV also existed in end-stage renal disease (ESRD) patients. METHO...

Snoring is a common sleep-related behaviour. Increased body mass index (BMI), cranio-facial anatomical features, and older age have been linked to the occurrence of snoring. While mostly middle-aged populations have been studied for the occurrence of snoring and sleep-related breathing abnormality, this study was designed to assess the subjective report of snoring and the objective measurement ...

The current study assessed sympathetic neuronal and vasomotor responses, total body oxygen consumption, and sensory thermal perception to identify thermoregulatory differences in younger and older human subjects during core cooling. Cold fluid (40 ml/kg, 4 degrees C) was given intravenously over 30 min to decrease core temperature (Tc) in eight younger (age 18-23) and eight older (age 55-71) in...

THE ARTICLE BY BUYSSE ET AL1 IN THIS ISSUE REPORTS ON A STUDY DESIGNED TO EXPLORE THE INFLUENCE OF THE CIRCADIAN SYSTEM ON SLEEP AND performance in older subjects. This topic is one of great interest, especially given the rapidly aging US population. Sleep complaints are a common feature of aging,2-4 so common that many older people fail to seek help from a medical professional.5 As several pre...

We measured leg blood flow (LBF), drew arterial-venous (a-v) blood samples, and calculated muscle O 2 consumption (VO 2), during incremental cycle ergometry exercise (15, 30, 99 W, and maximal effort (WR max)), in 9 sedentary younger (Y, 20 ± 1 yrs) and 9 sedentary older (O, 70 ± 2 yrs) males. LBF was preserved in the older subjects at 15 and 30 Watts. However, at 99 W and at maximal effort, le...

Spoken language processing in noisy environments, a hallmark of the human brain, is subject to age-related decline, even when peripheral hearing might be intact. The present study examines the cortical cerebral hemodynamics (measured by fMRI) associated with such processing in the aging brain. Younger and older subjects identified single words in quiet and in two multi-talker babble noise condi...

Pulse pressure rather than diastolic pressure is the best predictor of coronary heart disease risk in older subjects, but the converse is true in younger subjects. We hypothesized that this disparity results from an age-related difference in pressure amplification from the aorta to brachial artery. Data from 212 subjects age < 50 years and 230 subjects age > or =50 years were abstracted from a ...