A diagnosis of food allergies should be made based on the observation of allergic symptoms following the intake of suspected foods and the presence of allergen-specific IgE antibodies. The oral food challenge (OFC) test is the most reliable clinical procedure for diagnosing food allergies. Specific IgE testing of allergen components as well as classical crude allergen extracts helps to make a m...

BACKGROUND It is well known that atopic dermatitis (AD) is related to food hypersensitivity, although its prevalence varies among several studies according to age group, severity, country, survey time, and test method. OBJECTIVE To examine the prevalence and status of food hypersensitivity among childhood AD patients in Korea. METHODS A total of 95 patients were enrolled in the study. The h...

Food protein induced enterocolitis syndrome (FPIES) is a food-related non-IgE-mediated gastrointestinal hypersensitivity disorder. Atypical FPIES is characterized by the presence of specific IgE for the causative food. The guidelines suggested for diagnostic oral food challenge in pediatric patients affected by suspected FPIES are different from the ones for children with IgE-mediated food alle...

OBJECTIVES To determine tolerance rates to cow's milk and soy and to suggest guidelines for follow-up oral food challenges (FU-OFCs) in infantile food protein-induced enterocolitis syndrome (FPIES). METHODS The authors analysed the data of 23 patients with infantile FPIES who underwent two or more FU-OFCs and were followed up until over 2 years of age. The first FU-OFCs were performed at 6 mo...

© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org Diagnosis of food allergy requires thorough history and physical examination, and/or skin prick tests or serum immunoassays to determine food-specific IgE (sIgE) antibodies for IgEmediated food allergy. Double-blind placebo-controlled food...

BACKGROUND Double-blind placebo-controlled food challenge, DBPCFC, the gold standard for diagnosing food allergy, is time-consuming and potentially dangerous. A basophil allergen threshold sensitivity test, CD-sens, has shown promising results as a diagnostic tool in food allergy. OBJECTIVES To evaluate the reproducibility of oral peanut challenge and compare the outcome to CD-sens in peanut-...

Background Food allergy in children is increasing in prevalence and severity. To parents this may translate to deliberate food restriction especially to either highly allergenic foods or to unknown foods (food neophobia). These claims need to be evaluated by a good clinical history and if warranted, skin prick testing and food specific IgE assays. However neither of these is diagnostic of food ...

Background Food allergy in children is increasing in prevalence and severity. To parents this may translate to deliberate food restriction especially to either highly allergenic foods or to unknown foods (food neophobia). These claims need to be evaluated by a good clinical history and if warranted, skin prick testing and food specific IgE assays. However neither of these is diagnostic of food ...