Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...

Abstract: Background: The aim of this study was to enhance the solubility Natamycin, an antifungal agent used in fungal keratitis, through solid dispersion incorporated ophthalmic films with purpose avoid frequent dosing, period retention, and sustaining release for better patient compliance. Materials Methods: Firstly, dispersions were prepared by solvent evaporation method then, best formulat...

The aim of this investigation was to design and develop nanoemulsions (NEs) as novel ophthalmic delivery systems for brinzolamide (BZD). Phase behavior of quaternary systems composed of triacetin and CapryolTM 90 (selected oils, screened through the solubility studies), various surfactants (namely, Cremophor RH 40, Brij 35, Labrasol and tyloxapol), Transcutol P (as co-surfactant) an...

The Kenya Ophthalmic Programme (KOP) is a Ministry of Health (MOH) programme receiving administrative support from the Kenya Society for the Blind (KSB). It started as a small project in 1956 but has grown into a major National Programme rendering comprehensive eye care (CEC) through a network of about 70 Government and NGO static and outreach service delivery points scattered all over the coun...

The field of ocular drug delivery is one the most interesting and challenging fields for Formulation Scientists or Pharmacists. In ophthalmic in situ gel many polymers are used which form by various mechanisms like pH-sensitive thermo sensitive gel. We can make instead an solution to overcome problem low bioavailability. Some common diseases cured blepharitis, conjunctivitis, keratitis, trachom...

Levobetaxolol is a cardioselective beta-blocker that has been demonstrated to reduce intraocular pressure in patients affected with primary open-angle glaucoma and ocular hypertension. Levobetaxolol may be an effective neuroprotectant because of its great capacity to block sodium and calcium influx, which might confer a neuroprotective activity. Experimental and clinical studies have demonstrat...

An ageing population means that the incidence of people who are visually impaired will increase. However, extending the role of ophthalmic nurses will promote delivery of a more effective health service for these patients. Using Maslow's hierarchy of needs as a basis for addressing the care of patients with visual impairment is a means of ensuring that they receive high quality, appropriate car...

To comprehend the current challenges that French ophthalmic care is facing, one has first to appreciate the system and the changes that have occurred over the years leading to the current situation. French ophthalmic care is organized differently from its British and American counterparts and resembles its European neighbors. It follows a basic principle of the French medical practice which sho...