AIMS To investigate the patterns of concurrent sexual partnerships among young opiate users and sexual transmissibility of human immunodeficiency virus (HIV) in concurrent sexual partnerships in drug-use and sexual networks. DESIGN Cross-sectional design. PARTICIPANTS A total of 426 young opiate users in Yunnan, China. SETTING Young opiate users recruited from their network ties. MEASUR...

Editorials 83 The United Nations Office of Drugs and Crime in its 2012 World drug report estimates that 0.6% of the world's adult population – some 27 million people – are problem users of illicit drugs. 1 This represents about 10% of all people who used illicit drugs in 2011 and suggests that most people can use drugs recreationally without becoming dependent. What makes these 10% different is...

Objective: Craving for substance abuse is a usual and complicated problem in patients, with opioid addiction who are in opioid detoxifying process. Craving has been added as one of the diagnostic criteria of substance use disorders in DSM-5. The present trial aimed at comparing the effects of celecoxib versus ibuprofen in reducing pain and decreasing the desire to use opiates in patients underg...

BACKGROUND Despite intriguing observational cross-sectional data there are no longitudinal studies of opiate related arterial disease. As opiates act via P16INK4A/CDKN2A, and vascular ageing has been thought to be a surrogate for organismal ageing, the subject has far-reaching implications. METHODS Pulse Wave Analysis (PWA) by radial arterial tonometry (SphygmoCor) was performed on control an...

The consolidation of newly acquired memories involves the temporal transition from a recent, less stable trace to a more permanent consolidated form. Opiates possess potent rewarding effects and produce powerful associative memories. The activation of these memories is associated with opiate abuse relapse phenomena and the persistence of compulsive opiate dependence. However, the neuronal, mole...

Aripiprazole Treatment in the Adolescent Patients with Inhalants Use Disorders and Conduct Disorder: A Retrospective Case Analysis Pharmacologically, aripiprazole is a partial agonist at D2 and 5-HT1A receptors and an antagonist at 5-HT2A receptors with the different effect on dopaminerjic system from other antipsychotics. Partial agonists are effective for stimulants, opiate, cocaine and nicot...

background substance use among college students in iran is a serious problem. determining the pattern of substance use among university students is an important issue for implementing prevention and treatment programs. objectives the present survey attempts to determine the prevalence of substance usage and associated risk factors among the students of jahrom university of medical sciences and ...

post-operative pain and its management remains one of the most important issues in the field of surgery and health care system. on the other hand, opioid drug abuse has a large prevalence in iran. formalin test has been used as a method for assessing pain and analgesia in rats. in the present study, the post-operative pain in morphine addicted rats was compared with that of non-addicted ones us...

INTRODUCTION Suicide is closely linked to the substances use. Therefore it is very important to confirm the factors that affect the possibility of suicidal behavior. METHODOLOGY The survey included 200 respondents; 100 heroin addicts on the substitution program that attempted suicide and 100 opiate addicts who have not attempted suicide. The evaluation included a questionnaire with socio-demo...