نتایج جستجو برای: optimization of expression
تعداد نتایج: 21262276 فیلتر نتایج به سال:
due to project evaluation complexity and resource constraints, the project portfolio optimization is numerous decision making challenges. hence, many researches have been done to introduce model and methods for portfolio optimization. but most of them have not considered the interaction between projects. considering the interactions between projects increase complexity of portfolio optimization...
Abstract Background and Objective: the inhibition of tumor-associated angiogenesis can significantly reduce the tumor proliferation. The basic fibroblast growth factor (bFGF), an important angiogenic factor, is considered as a potential therapeutic target for cancer therapy. The purpose of this study was evaluating, designing and construction of new recombinant DNA molecule in order to ha...
this study is focused on the development of a systematic computational approach which implements genetic algorithm (ga) to find the optimal rigorous kinetic models.a general kinetic model for hydrogenolysis of dibenzothiophene (dbt) based on langmuir-hinshelwood type has been obtained from open literature. this model consists of eight continuous parameters(e.g., arrhenus and van't hoff paramet...
background: breast cancer is one of the most prevalent malignancies among women in various countries. her2 overexpression, which is due to different reasons, occurs in 20-30% of breast cancers. her2 gene encodes an 185kda transmembrane glycoprotein with 1255 amino acids. this active product triggers downstream intracellular signaling pathways inducing cell proliferation and cell survival. these...
Background: Culture media enrichment through the addition of protein hydrolysates is beneficial for achieving higher protein expression. Methods: In this study, designing the optimum mixture of four soy and casein-derived hydrolysates was successfully performed by design of experiment and specific productivity increased in all predicted combinations. Protein profile of recombinant CHO (rCHO) ce...
A compact fin-tube heat exchanger is used to transfer current fluid heat inside the tubes into the air outside. In this study, entropy production and optimized Reynolds number for finned-tube heat exchangers based on the minimum entropy production have been investigated. As a result, the total entropy of compact heat exchangers, which is the summation of the production rate of fluid entropy ins...
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