Messenger RNAs containing premature stop codons are generally targeted for degradation through nonsense-mediated mRNA decay (NMD). This mechanism degrades aberrant transcripts derived from mutant genes containing nonsense or frameshift mutations. Wild-type genes also give rise to transcripts targeted by NMD. For example, some wild-type genes give rise to alternatively spliced transcripts that a...

conclusions results showed that the boiled anethum graveolens seeds was effective on labor induction. results case group had a significantly better bishop score following the intervention compared to the control group. the mean duration of active phase, second and third stages of labor were significantly lower in the case group. the control group had shorter latent phase than the case group. pa...

Quantum Toda lattice may solved by means of the Representation Theory semisimple Lie groups, or alternatively using technique Inverse Scattering Method. A comparison two approaches, which is purpose present review article, sheds a new light on and leads to number challenging questions.

AIM To analyze the alternatively spliced variant of Stam2 mRNA and determine its distribution in mouse tissues. METHODS We identified a novel alternatively spliced exon by cloning and sequencing of Stam2 cDNA obtained from tissue samples of 3-5 months old male C57Bl/6NCrl mice. The sequence of the alternatively spliced exon was analyzed by bioinformatic tools. The tissue distribution of diffe...

Recent genome-wide studies have demonstrated that fungi possess the machinery to alternatively splice pre-mRNA. However, there has not been a systematic categorization of the functional impact of alternative splicing in a fungus. We investigate alternative splicing and its functional consequences in the model mushroom forming fungus Schizophyllum commune. Alternative splicing was demonstrated f...

Effective protocols are introduced for parthenogenesis activation in oocytes. Hydrostatic pressure can act as a mechanical stimulator that rearranges egg contents, leading to new structural or molecular combination. Alternatively, mechanical stimulation could stimulate a mechanically-gated process, such as opening or closing of stretch activated ion channels. This study, investigated the use of...