OBJECTIVES To evaluate the awareness of oral cancer, its risk factors and to estimate the prevalence of risk factors in a high-risk semi-urban population in India. METHODS A questionnaire-based survey was carried out by house-to-house interview on a single day by 120 health volunteers. The data were analyzed using SPSS 11.0 software for links between prevalence of risk factors and oral cancer...

Oral cancer refers to all malignancies that arise in the oral cavity, lips and pharynx, with 90% of all oral cancers being oral squamous cell carcinoma. Despite the recent treatment advances, oral cancer is reported as having one of the highest mortality ratios amongst other malignancies and this can much be attributed to the late diagnosis of the disease. Saliva has long been tested as a valua...

Within a single tumor clone, cells have significantly different abilities to proliferate and form new tumors. This has led to the hypothesis that most cells in a cancer have a limited ability to divide and only a small subset of distinct cells, the cancer stem cells (CSCs), has the capacity to self-renew and form new tumors . It has been proposed that the development of tumors is based exclusiv...

Cancers of the oral cavity (lip, tongue, salivary glands, and other sites in the mouth) and pharynx account for about 3% of the cancers diagnosed in the United States each year. About 30,000 new cases are diagnosed and over 8,000 people die from the disease each year (1). The 1990-1994 mortality rate for oral cancers was 2.5 per 100,000, ranking Oregon 37th among the states. Overall, the five-y...

Oral cancer is the sixth common tumour worldwide [1]. Oral cancer is the fourth leading cause of cancer death for males [2]. Oral squamous cell carcinoma (OSCC) is the most common neoplasia and is found frequently in oral cavity in the cheek, gingiva and tongue [3]. Although cigarette and alcohol are considered as two major etiological factors of oral carcinogenesis [4], occurrence of oral canc...

Oral cancer accounts for the majority of the cancer in South East Asian region and especially in the Indian subcontinent. If diagnosed at an early stage the disease is reported to have a better prognosis. Sialochemistry involving antioxidants has recently gained importance for oral cancer risk assessment because of its non-invasive nature. The aim of this study was to estimate the levels of glu...

Oral cancer accounts for the majority of the cancer in South East Asian region and especially in the Indian subcontinent. If diagnosed at an early stage the disease is reported to have a better prognosis. Recently studies have been conducted to determine the levels of serum antioxidants for risk assessment of oral cancer. The aim of this study was to estimate the levels of glutathione in serum ...

within a single tumor clone, cells have significantly different abilities to proliferate and form new tumors. this has led to the hypothesis that most cells in a cancer have a limited ability to divide and only a small subset of distinct cells, the cancer stem cells (cscs), has the capacity to self-renew and form new tumors . it has been proposed that the development of tumors is based exclusiv...