BACKGROUND Most human immunodeficiency virus positive patients now have a longer life expectancy, with the advent of highly active antiretroviral therapy. However, they are now at increased risk of developing a malignancy during their lives. AIM To investigate the age at which oral squamous cell carcinoma presents in patients infected with human immunodeficiency virus. STUDY DESIGN Prospect...

The objective of this study was to provide a baseline data on the pattern of oral squamous cell carcinoma in Karachi. The retrospective cross sectional study was conducted. The patients of oral squamous cell carcinoma were examined from January 2007December 2010 at oral maxillofacial department, Darul Sehat Hospital Karachi. All retrievable case files were obtained and necessary data were extra...

− New treatment approaches are needed to improve the effectiveness of oral cancer treatment, since surgical resection of the tumor in oral region causes various oral dysfunctions. The molecular biology of oral cancer has been progressively delineated. Concurrently, gene therapy techniques have been developed that allow targeting or replacement of dysfunctional genes in cancer cells, offering th...

Aim: To determine the Frequency and Pattern of Presentation Oral Squamous Cell Carcinoma its Predisposing Factors in Patients Presented to Nishtar Institute Dentistry. Study design: Cross sectional study. Place Duration Study: was conducted from Aug 2021 Jan 2022 at Methodology: A total 100 patients were included. aged between18-80 years males females included whom presented with oral squamous ...

BACKGROUND CD44 is a transmembrane receptor found on many different benign and malignant cells. Hyaluronan (HA), a major component of the extracellular matrix, is the primary ligand for CD44 receptors. In cancer cells, HA interaction with CD44 promotes multiple signaling pathways that influence tumor cell progression behaviors in a variety of solid tumors. Increasing evidence indicates that HA ...

Objective: Oral Squamous Cell Carcinoma (OSCC), which is the sixth most prevalent type of cancer across globe caused by cigarette smoking, smokeless tobacco use, excessive and extreme alcohol oral trauma, HPV (Human Papilloma Virus) infection as well genetic mutations. AIF-1(Allograft Inflammatory Factor) has been identified an inflammatory response modulator, its increased expression linked to...

For citation purposes: Lanzer M, Zemann W, Lübbers T, Kruse A, Reinisch S. Do patients with oral and oropharyngeal squamous cell carcinoma benefit from elective contralateral neck dissection? A long-term analysis. Head Neck Oncol. 2012 Oct 31;4(3):70. Licensee OA Publishing London 2012. Creative Commons Attribution License (CC-BY) Abstract Objectives Oral and oropharyngeal squamous cell carcino...

Background/Aims and Objectives: Inflammatory mediators from ongoing oral infection induce intense immune response that could lead to the carcinogenesis as well progression of pathogenesis systemic diseases. Development prostatic carcinoma presence urinary symptoms may be linked problems.

Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chances of curing the disease. This study aims to describe a clinical case of oral squamous cell carcin...