Wegener's granulomatosis is a multisystemic granulomatous vasculitis that predominantly affects the airways and the kidneys, but may affect any organ. Otorhinolaryngological manifestations may be oral ulcers, gingival swelling or septal perforations that can cause saddle nose deformities, rhinitis, sinusitis and hearing loss. The oral ulcers usually occur when the disease is advanced. Renal inv...

Behçet's disease is a multisystem inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. The cause of Behçet's disease remains unknown, but epidemiologic findings suggest that an autoimmune process is triggered by an environmental agent in a genetically predisposed individual. An infectious agent could operate through molecular mimicry,...

BACKGROUND Mycobacterium chelonae is an important human pathogen and should be considered when a physician is faced with nonhealing cutaneous wounds, including ulcers of the lower leg. METHODS The medical literature was searched from 1965 to the present using the key words "Mycobacterium chelonae" and "leg ulcers." A case of Mycobacterium chelonae infection is reported. RESULTS AND CONCLUSI...

background: endoscopic therapies can decrease the morbidity of patients with high risk peptic ulcer. the aim of this study was to evaluate the beneficial effects of oral omeprazole therapy in patients with bleeding peptic ulcer who received combined endoscopic treatment (epinephrine injection and argon plasma coagulation). materials and methods: eighty six patients with bleeding from gastric, d...

tuberculosis is a major cause of morbidity and mortality worldwide. it is a chronic granulomatous disease that can affect any part of the body, including the oral cavity. oral lesions of tuberculosis, though uncommon, are seen in both the primary and secondary stages of the disease. this article presents a case of tuberculosis of the buccal mucosa, manifesting as non-healing, non-painful ulcer....

BACKGROUND Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries. However, it is not yet available in China and has not been generally accepted in clinical treatment. The aim of this study was to explore the effectiveness of amlexanox oral adhesive pellicles in the treatment of minor recur...

AIM Recurrent aphthous ulceration is the most commonly known oral mucosal disease. Quercetin is a useful therapeutic agent for the treatment of colitis and gastric ulcer. The objective of this study was to determine the effect of topical application of quercetin in the treatment of minor aphthous ulcers. METHODS AND MATERIALS Forty male patients with no known pathology of the oral mucosa othe...

A 21-year-old man presented with chronic nonspecific conjunctivitis for 5 months. There were multiple oral ulcers and vesicular lesions at his face. B iopsy was done at the ves icula r les ion and the pathological report was compatible with cicatricial pemphigoid. Although the patient did not have any esophageal symptoms, EGD was performed due to patient’s preference. Endoscopic f indings showe...