As we approach the end of our 22nd year as the pioneering and preeminent Open Access journal in the field of organic chemistry and natural products, time has come to formally announce what has been the de facto reality of the journal for the past few years, the expansion of the range of topics we cover.[...].

It’s the night before his organic chemistry examination, but John isn’t ready for the test. Sure, he studied all week for the test, but he still doesn’t have a firm grasp of all the material and he knows his professors wouldn’t be happy with him if he woke them up now, at 1:30 A.M. So, he sits down at his PC and launches his browser, guiding it to the “Question Generator” homepage where he logs...

Automation of discontinuous elementary operations specific to organic chemistry on a laboratory scale was developed as early as 1970 by the Roussel UclafCompany [1]. A modular system was chosen, because of the diversity of possible operations. Each module governs a simple operation: measuring and comparing a temperature, controlling a pump, etc. These elements communicate with one another throu...

Over the decades the Smiles rearrangement and its variants have become essential synthetic tools in modern synthetic organic chemistry. In this mini-review we summarized some very recent results of the radical version of these rearrangements. The selected examples illustrate the synthetic power of this approach, especially if it is incorporated into a domino process, for the preparation of poly...

Visualization and other forms of spatial cognition are considered fundamental to learning and problem solving in science. This assumption is especially prevalent in organic chemistry where imagistic reasoning is considered to be a primary cognitive activity. While previous research has shown that students are aware of several analytical heuristics and imagistic strategies for problem solving, t...

Molecular complexity for a synthetic organic chemist is difficult to define, though intuitively known. Despite the importance of this concept, the quantitative assessment of complexity within organic chemistry has remained a challenge. We report here on the development of an approach for generating a unique complexity index, which is reflective of both intrinsic molecular complexity and extrins...

Mohaddeseh Seddighi was born in Rasht, Guilan, I. R. Iran (1985). She received B.Sc. in applied chemistry from Isfahan University of Technology (IUT) (2007) and his M.Sc. in organic chemistry from Isfahan University of Technology (2010) under the direction of Professor Abdol. R. Hajipour. She began her Ph.D. studies at University of Guilan under supervision of Professor Farhad Shirini from 2011...

Mohaddeseh Safarpoor Nikoo Langroodi was born in Langrood, Guilan, I.R. Iran. She received B.S. in chemistry from Shahid Beheshti University (2006) and his M.S. in organic chemistry from University of Guilan (2010) under the direction of Professor Farhad Shirini. After two years, she began her Ph.D. studies at University of Guilan under supervision of Professor Farhad Shirini. Her current resea...

Mohaddeseh Seddighi was born in Rasht, Guilan, I. R. Iran (1985). She received B.Sc. in applied chemistry from Isfahan University of Technology (IUT) (2007) and his M.Sc. in organic chemistry from Isfahan University of Technology (2010) under the direction of Professor Abdol. R. Hajipour. She began her Ph.D. studies at University of Guilan under supervision of Professor Farhad Shirini from 2011...