PURPOSE In longitudinal oncological and brain PET/CT studies, it is important to understand the repeatability of quantitative PET metrics in order to assess change in tracer uptake. The present studies were performed in order to assess precision as function of PET/CT system, reconstruction protocol, analysis method, scan duration (or image noise), and repositioning in the field of view. METHO...

Severely impacted and dilacerated incisors are rarely considered for surgical exposure because they may not respond favorably to orthodontic extrusion. These incisors are often extracted, resulting in the need for tooth replacement; however, prosthetic solutions are limited in growing patients. Transalveolar autotransplantation of an impacted incisor may be the only method to preserve the natur...

OBJECTIVE To evaluate morphologic characteristics of occlusion (contact points, contact areas, and frequency of contact) in clinically successful patients 1 year after orthodontic and surgical-orthodontic therapy followed by passive retention. MATERIALS AND METHODS Twenty-two orthodontic and 18 surgical-orthodontic patients were analyzed. All patients were treated with standard edgewise techn...

BACKGROUND In sports involving pivoting and landing, female athletes suffer knee injury at a greater rate than male athletes. HYPOTHESES Proprioceptive deficits in control of the body's core may affect dynamic stability of the knee. Female, but not male, athletes who suffered a knee injury during a 3-year follow-up period would demonstrate decreased core proprioception at baseline testing as ...

Drug development is expensive and prone to failure. It is potentially much less risky and expensive to reuse a drug developed for one condition for treating a second disease, than it is to develop an entirely new compound. Systematic approaches to drug repositioning are needed to increase throughput and find candidates more reliably. Here we address this need with an integrated systems biology ...

DENNIS J. WEBER II: Effectiveness and Efficiency of a Customized Versus Conventional Orthodontic Bracket System (Under the direction of Dr. Lorne Koroluk) The goal of this investigation was to compare the clinical effectiveness and efficiency of a customized versus a conventional orthodontic bracket system. Pre-treatment and post-treatment diagnostic records of 11 patients treated with conventi...

The present study proposed a two-step drug repositioning method based on a protein-protein interaction (PPI) network of two diseases and the similarity of the drugs prescribed for one of the two. In the proposed method, first, lists of disease related genes were obtained from a meta-database called Genotator. Then genes shared by a pair of diseases were sought. At the first step of the method, ...

The objective of this study was to evaluate and compare the periodontal status of orthodontic patients and non-orthodontic patients, aged 15-28 years, of both genders. The cross-sectional study included 100 orthodontic and 100 non-orthodontic patients evaluated using a Community Periodontal Index for Treatment Need (CPITN) probe on the index teeth. A questionnaire was distributed to the partici...

The aim of the present study was to evaluate oral hygiene status of patients receiving fixed orthodontic treatment and to monitor it longitudinally. Main sample consisted of one hundred patients with an age range of 12-25 years, having a full complement of permanent dentition, reporting to the orthodontic department of the Punjab Dental Hospital, Lahore. Patients having major medical problems, ...