The New York City Health and Nutrition Examination Survey (NYC HANES) was a population based sample of New York City adults collected in 2004. To determine seroprevalence to 2009 H1N1 antibody, as well as viruses from prior pandemics, a 400 person subsample of repository serum was selected for inclusion in the study, representing persons who were 23 or older in 2004. All specimens were tested b...

In the spring of 2009, a novel influenza A virus of the H1N1 subtype emerged that transmitted efficiently among humans; by June of 2009, the outbreak reached pandemic status. The pandemic virus possesses six viral RNA segments from so-called triple reassortant swine viruses that emerged in North American pig populations in the late 1990s and two viral RNA segments from Eurasian avian-like swine...

We analyzed the complete genome sequence containing the 3' and 5' noncoding regions (NCRs) of H3N2 canine influenza virus (CIV) with the matrix gene from the pandemic A/H1N1 virus, which will provide a better understanding of the pathogenesis, transmission, and evolution of variant CIV.

A more realistic mathematical influenza model including dynamics of Twitter, which may reduce and increase the spread of influenza, is introduced. The basic reproductive number is derived and the stability of the steady states is proved. The existence of Hopf bifurcation are also demonstrated by analyzing the associated characteristic equation. Furthermore, numerical simulations and sensitivity...

Although predicting which influenza virus subtype will cause the next pandemic is not yet possible, public health authorities must continually assess the pandemic risk associated with animal influenza viruses, particularly those that have caused infections in humans, and determine what resources should be dedicated to mitigating that risk. To accomplish this goal, a risk assessment framework wa...

[This corrects the article DOI: 10.1371/journal.ppat.1006780.].

The appearance of the new Asian influenza virus in early 1957 and its subsequent rapid spread throughout the world stimulated renewed interest in the epidemiology of influenza. For the first time since identification of the etiologic agents of this disease the opportunity presented itself for study of its pandemic form by specific microbiological tests. The results of a number of such studies c...

Since the isolation of influenza virus in 1933, a great deal of work was carried out in order to develop influenza vaccines and improve these fundamental tools of prevention in terms of production, quality control, safety and tolerability, and immunogenicity. The paper summarizes the cornerstones of the continuous evolution of influenza vaccines and the most recent and promising developments in...