BACKGROUND Orthopedic injuries occurring in Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) are complicated by infections with multidrug resistant bacteria. We describe demographics and microbiology of OIF/OEF casualties with primary and recurrent osteomyelitis. METHODS A retrospective cohort study was performed of OIF/OEF casualties admitted to our facility from February 1, 2003 to A...

HYPOTHESIS For critically injured patients, a limited course of antibiotics is as effective as a prolonged course in preventing sepsis and organ failures. DESIGN Prospective nonrandomized study. SETTING Surgical intensive care unit (SICU) of an academic hospital with a level I trauma center. PATIENTS A population of 250 trauma patients who required an operation and SICU stay of 3 days or ...

INTRODUCTION The aim of this study was to evaluate the clinical outcomes and safety of daptomycin therapy in patients with serious Gram-positive infections. METHODS Patients were enrolled in the European Cubicin(®) Outcomes Registry and Experience (EU-CORE(SM)), a non-interventional, multicenter, observational registry. The real-world data were collected across 18 countries (Europe, Latin Ame...

Introduction Debridement, antibiotics and implant retention (DAIR) is an attractive treatment option for prosthetic joint infections (PJIs). However, reported success rates predictors of DAIR failure vary widely. The primary aim this study to report the outcome in patients with hip knee PJIs receiving short course antibiotic therapy. secondary identify risk factors failure. Methods We performed...

During a 6-week period, 10 patients were admitted to a hospital for treatment of knee or shoulder joint infections due to Serratia species. Isolates from eight patients were identified as Serratia marcescens with identical biochemical characteristics and antibiotic susceptibility patterns. Before the onset of infections, all patients had been treated by two orthopedic surgeons who shared an off...

Objective. The evolution of new prosthetic and osteosynthesis devices has led to better outcomes therefore more frequent surgical indications. As a consequence, an increased incidence complications such as infections or aseptic loosening in orthopedic trauma surgery are being recorded general population. MicroDTTect is quick simple system that useful detect low grade bio-film related infections...