Microliths and ossification were found in the lungs of a 12-year-old bitch suffering from compound mammary gland tumor which has disseminated in the inguinal lymph node glands and the lungs. Pulmonary ossification appeared grossly as irregular stony sharp particles which infiltrated the lung tissue and were readily recognizable from under the pleura as grayish sharp protruding particles. Micros...

The clinical, radiologic, and histologic features of ossification and calcification of the ligamentum flavum were studied in 18 patients. Ossification (15 patients) usually occurred in the lower thoracic spine in men of various ages, while calcification (three patients) was found exclusively in the cervical region of older women. Histologic examinations of ossification showed mature lamellar bo...

There is no report that describes in detail the radiological and intraoperative findings of rickets with symptomatic cervical ossification of the posterior longitudinal ligament. Here, we describe a case of X-linked hypophosphatemic rickets with cervical ossification of the posterior longitudinal ligament presenting unique radiological and intraoperative findings. The patient presented progress...

Pulmonary ossification is an idiopathic disorder that presents with the formation of mature bone in the pulmonary parenchyma. This is a very rare entity that occurs in conjunction with busulfan therapy as well as with a number of diseases including chronic bronchitis, cystic fibrosis, congestive heart failure, myositis ossificans, and idiopathic interstitial fibrosis. It is usually seen in olde...

True ossification of the face spaces is a very rare clinical entity. We present a rare case of unilateral ossification of infratemporal space the in an 11-years old male with swelling in the right temporal and orbital area. His medical history was unremarkable. Radiographic evaluation with spiral CT scan revealed separated ossified particles inside of infratemporal space. After 2 separate proce...

Homozygous mice with a null mutation in the MMP-9/gelatinase B gene exhibit an abnormal pattern of skeletal growth plate vascularization and ossification. Although hypertrophic chondrocytes develop normally, apoptosis, vascularization, and ossification are delayed, resulting in progressive lengthening of the growth plate to about eight times normal. After 3 weeks postnatal, aberrant apoptosis, ...

Ossification of the posterior longitudinal ligament in the cervical region is generally regarded as a rare disease, though a Japanese series of 185 cases has been reported. The main symptoms arise from a myelopathy, the degree of which varies from moderate to severe, due to stenosis of the spinal canal. In order to clarify the relationship between the severity of symptoms and the cross-sectiona...

A case of metastatic colorectal carcinoma with heterotopic ossification is described. Objective Morphoproteomic analysis was performed to help define the histogenesis of the heterotopic ossification in this context. Design Immunohistochemical stains for Gli2, α-SMA, SPARC (osteonectin), and nestin were performed and the expression level (chromogenic signal intensity) and subcellular compartment...

The problem of objectivity in histopathology is illustrated by an attempt to determine the normal range and significance of two observations, placental weight and secondary ossification, made in perinatal pathology. Neither offered a satisfactory estimation of fetal maturity. The placental weight provided little evidence of any primary placental dysfunction: the placenta was very small in assoc...

Heterotopic mesenteric ossification is extremely rare. Here, we report a case of heterotopic mesenteric ossification in a 60-year-old man who underwent a Hartmann procedure with ileostomy for treatment of diverticulitis spanning the descending and sigmoid colon about 2 months ago. Imaging studies of the abdomen, including roentgenography, ultrasound, and computed tomography (CT) revealed diffus...