نتایج جستجو برای: ovarian development

تعداد نتایج: 1489267  

2017
Yanqing Wu Yiyang Li Xinghui Liao Zhengchao Wang Rui Li Shuang Zou Ting Jiang Bingbing Zheng Ping Duan Jian Xiao

Diabetes triggers abnormal ovarian follicular development and consequently leads to infertility. Here, we established a type 2 diabetes mouse model by feeding with high fat diet (HFD) for 15/20 weeks and assessed the effect of diabetes on follicular development and ovarian angiogenesis. After fed with HFD for 15 weeks, mice had the characteristics of type 2 diabetes, which was much more serious...

Journal: :Environmental Health Perspectives 1987
N J MacLachlan

The histologic appearance of the ovaries and persistence of corpora lutea vary considerably among domestic animals, particularly between spontaneous and induced ovulators. The seasonally polyestrous mare has a variety of unique characteristics in ovarian structure and general reproductive function. Among the anomalies of ovarian development is the bovine freemartin with gonads containing a mixt...

Journal: :Frontiers in bioscience 2013
Agnieszka Lech Teodora Daneva Shina Pashova Hristo Gagov Robert Crayton Wojciech Kukwa Anna M Czarnecka Cezary Szczylik

Ovarian cancer is characterized by the highest mortality rate among gynecologic malignancies. Therefore, there is a growing need for innovative therapies and techniques for monitoring and prevention of this disease. The exact cause of most ovarian tumors usually remains unknown. Ovarian cancer is believed to be caused by a range of different variables. This review is an attempt to summarize som...

Journal: :American journal of epidemiology 2007
Ellen T Chang Valerie S Lee Alison J Canchola Christina A Clarke David M Purdie Peggy Reynolds Hoda Anton-Culver Leslie Bernstein Dennis Deapen David Peel Rich Pinder Ronald K Ross Daniel O Stram Dee W West William Wright Argyrios Ziogas Pamela L Horn-Ross

Dietary phytochemical compounds, including isoflavones and isothiocyanates, may inhibit cancer development but have not yet been examined in prospective epidemiologic studies of ovarian cancer. The authors have investigated the association between consumption of these and other nutrients and ovarian cancer risk in a prospective cohort study. Among 97,275 eligible women in the California Teacher...

Journal: :Brazilian journal of biology = Revista brasleira de biologia 2005
S Chellappa M R Câmara J R Verani

The Neotropical red discus fish, Symphysodon discus, originates from the Amazonian basin and has a discoid body. Although this species is popularly used in aquaria and is exported as an ornamental fish, it has not been intensively studied. The purpose of this work was to study the morphological and histological aspects of the ovarian development in the red discus. Forty females of S. discus of ...

2014
Gerasimos Aravantinos Dimitrios Pectasides

As increased angiogenesis has been linked with the progression of ovarian cancer, a number of anti-angiogenic agents have been investigated, or are currently in development, as potential treatment options for patients with advanced disease. Bevacizumab, a recombinant monoclonal antibody against vascular endothelial growth factor, has gained European Medicines Agency approval for the front-line ...

Journal: :Journal of experimental zoology. Part A, Ecological genetics and physiology 2015
Anna L M Macagno Oliver M Beckers Armin P Moczek

Fecundity is a fundamental determinant of fitness, yet the proximate developmental and physiological mechanisms that enable its often rapid evolution in natural populations are poorly understood. Here, we investigated two populations of the dung beetle Onthophagus taurus that were established in exotic ranges in the early 1970s. These populations are subject to drastically different levels of r...

Journal: :International journal of molecular medicine 2015
Haiyan Jiang Lei Qi Feiran Wang Zhichao Sun Zhongwei Huang Qinghua Xi

Semaphorin 3A (SEMA3A) was initially identified to play an important role in axonal guidance. Recently, SEMA3A has also been considered as a candidate tumor suppressor, since it is often downregulated in numerous types of cancer, including prostate cancer, breast cancer and glioma. However, the biological role of SEMA3A in ovarian cancer is not clear. In the present study, the expression of SEM...

2016
Suzan Wadi Aaron R. Tipton Jill A. Trendel Sadik A. Khuder Deborah J. Vestal

Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovarian cell lines. Forced expression of hGBP-1 in SKOV3 ovarian cancer cells protects them from paclitaxel-induced cell death. However, prior ...

Journal: :Human reproduction update 2008
B C J M Fauser K Diedrich P Devroey

Ovarian stimulation is applied in the clinic to restore mono-ovulatory cycles in anovulatory women (ovulation induction) or to induce the development of multiple dominant follicles for assisted reproduction. Ovarian response is the endocrine and follicular reaction of the ovaries to stimulation. Achieving an appropriate ovarian response to anti-estrogens or exogenous gonadotrophins is central t...

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