STUDY QUESTION What alters cardiovascular and metabolic risk factors with aging in women with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER Lipid parameters, mainly low-density lipoprotein (LDL) cholesterol, increase with aging, but not in women who attain ovulatory cycles. WHAT IS KNOWN ALREADY Cardiovascular and metabolic parameters tend to increase with aging, but this has not been sh...

Polycystic ovary syndrome (PCOS) is a frequent disorder, affecting approximately 5-10% of infertile women. It can represent more than 80% of cases of infertility due to anovulation. The main goal of treatment is the induction of mono-ovulatory cycles. A pragmatic management of infertility in PCOS will allow most patients to conceive. Weight loss and clomiphene citrate (CC) are the first-line co...

the main objective of an ecosystem sustainable management is to preserve itscapacity to respond and adapt to current disturbances and/or future changes, and maintain theprovision of environmental goods and services. two very important properties linked to thisobjective are the ecosystem resilience and resistance to disturbance factors. the objective ofthis paper is to recommend conceptual modif...

background: chemicals are among risk factors that can affect women's reproductive system. this study is aimed to investigate the association of occupational exposure to a mixture of organic solvents with menstruation disturbances and hormonal changes among female workers. methods : female workers of a pharmaceutical company were divided into three groups of non-exposed, low-exposed and highly-e...

Infertility is the inability to conceive following 1 year of unprotected intercourse in cases where the female is ≤35 years of age or following 6 months of unprotected intercourse for women >35 years of age. The female factor infertility is found in 40% of cases, the male in 20% of cases and the both male and female factors in 20% of cases. Female factors can further be divided into tubal (40%)...

Background: Infertility is defined as the inability to conceive after one two years of unprotected intercourse. It types: primary infertility and secondary 5On basis etiopathology divided into five groups: unexplained (28%), male factor (24%), ovarian dysfunction (21%), tubal (14%) others (13%). Luteinizing hormone (LH) follicle-stimulating (FSH) are integral parts neural endocrine interchange ...

BACKGROUND Prostaglandins (PG), produced by the follicle just before ovulation, appear to act locally to promote follicle rupture and oocyte release. METHODS To determine whether administration of PG synthesis inhibitor directly into the primate follicle would prevent ovulatory events, serum estradiol was used to predict the day of the ovulatory LH surge in rhesus monkeys. On the day before o...

Granulosa cells in a mature ovarian follicle have an abundance of LH/hCG receptors that respond rapidly to an ovulatory surge in gonadotropins. Within minutes, membrane signal transduction sets in motion metabolic changes that lead to follicular rupture. This study provides evidence that the initial ovarian response to such an ovulatory stimulus includes induction of the immediate-early transcr...