Chocolate is a widely appreciated foodstuff with historical appreciation as food from the gods. In addition to its highly palatable taste, it rich source of (poly)phenolics, which have several proposed salutogenic effects, including neuroprotective anti-inflammatory, anti-oxidant and cardioprotective capabilities. Despite known benefits this ancient foodstuff, there paucity information on effec...

Particulate matter (PM) air pollution has a significant impact on human morbidity and mortality; however, the mechanisms of PM-induced toxicity are poorly defined. A leading hypothesis states that airborne PM induces harm by generating reactive oxygen species in and around human tissues, leading to oxidative stress. We report here a system employing a microfluidic electrochemical sensor coupled...

Sequelae of prematurity triggered by oxidative stress and free radical-mediated tissue damage have coined the term "oxygen radical disease of prematurity". Caffeine, a potent free radical scavenger and adenosine receptor antagonist, reduces rates of brain damage in preterm infants. In the present study, we investigated the effects of caffeine on oxidative stress markers, anti-oxidative response...

8 ABSTRACT: Particulate matter (PM) air pollution has a 9 significant impact on human morbidity and mortality; 10 however, the mechanisms of PM-induced toxicity are poorly 11 defined. A leading hypothesis states that airborne PM induces 12 harm by generating reactive oxygen species in and around 13 human tissues, leading to oxidative stress. We report here a 14 system employing a microfluidic e...

nanofibrous scaffolds produced by electrospinning have attracted much attention, recently. aligned and random nanofibrous scaffolds of poly (vinyl alcohol) (pva), poly (ε-caprolactone) (pcl) and nanohydroxyapatite  (nha) were fabricated by electrospinning method in this study. the composite nanofibrous scaffolds were subjected to detailed analysis. morphological investigations revealed that the...

BACKGROUND Skin forms an important part of human innate immune system. Wrinkles, thinning and roughening of skin are some of the symptoms that affect the skin as it ages. Reactive oxygen species induced oxidative stress plays a major role in skin aging by modulating the elastase enzyme level in the skin. Extrinsic factors that affect skin aging such as UV radiation can also cause malignant mela...

The majority of chronic liver diseases are accompanied by oxidative stress, which induces apoptosis in hepatocytes and liver injury. Recent studies suggest that oxidative stress and insulin resistance are important in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and the pathophysiology of diabetes complications. Metformin has been shown to be hepatoprotective in the insulin-resi...