Background and aimsThe accumulation of fat increases the formation lipid peroxides, which are partly scavenged by alpha-tocopherol (α-TOH). Here, we aimed to investigate associations between different measures (abdominal) levels urinary α-TOH metabolites in middle-aged individuals.Methods resultsIn this cross-sectional analysis Netherlands Epidemiology Obesity study (N = 511, 53% women; mean [S...

Carbamylated LDL (cLDL) is a potential atherogenic factor in chronic kidney disease (CKD). However, whether elevated plasma cLDL associates with atherosclerosis in vivo is unknown. Here, we induced CKD surgically in apolipoprotein E-deficient (ApoE(-/-)) mice fed a high-fat diet to promote the development of atherosclerosis. These mice had two- to threefold higher plasma levels of both oxidized...

The role of oxidized lipids in cardiovascular diseases (CVD) has been investigated over the last three decades extensively. A number of studies have been carried out on the mechanisms, and pathways leading to the arterial atherosclerosis. These studies originated from the oxidation hypothesis of the atherosclerosis which was originally proposed more than 25 years ago (Steinberg et al., 1989), a...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : recently autologous fat tissue transfer has gained much popularity. on the other hand, applying the transferring methods with a higher survival rate is still controversial. the aim of this study is to compare dermis-fat graft and dermal-fascia-fat graft. methods : this animal study was conducted in 2008-2009. ...