Hypercholesterolemia is associated with impairments in endothelium-dependent vascular relaxations. Paradoxically, endothelial production of nitrogen oxides is increased in early stages of hypercholesterolemia. Prior work has shown that oxidized low density lipoprotein (LDL) has both stimulatory and inhibitory effects on endothelial nitric oxide synthase expression (eNOS) and has focused on lyso...

Foods are mixed with saliva in the oral cavity and swallowed. While staying in the stomach, saliva is contentiously provided to mix with the ingested foods. Because a salivary component of nitrite is protonated to produce active nitrous acid at acidic pH, the redox reactions of nitrous acid with phenolic compounds in foods become possible in the stomach. In the reactions, nitrous acid is reduce...

In this study, nanostructured ZnO arrays were synthesized by an accessible thermal oxidation (TO) methodology. The Zn films chemically etched with nitric acid (HNO3) and then oxidized in a furnace at 500 °C for 5 h. Two different morphologies achieved modifying the HNO3 concentration etching process: (a) grass-like nanostructures (b) rod-like nanostructures, process solution 2 8 M concentration...

The interaction between low density lipoproteins (LDL) and platelets might play a central role in the development of atherosclerosis in diabetes. The aim of the present study was to investigate whether the glycation of LDL is associated with modifications of their physico-chemical and functional properties and to study the action of glycated LDL (glycLDL) on platelets. LDL and platelets were is...

Effective solid acid catalysts play a key role to produce high-quality biodiesel through triglyceride transesterification. The present work describes a facile technique for the synthesis of a high-performing sulfonated multi-walled carbon nanotube (S-MWCNTs) solid acid catalyst for fatty acid ethyl ester (biodiesel) production. The results indicated that S-MWCNTs possessed high acidity due to t...

Insulin-degrading enzyme (IDE) is a thiol sensitive peptidase that degrades insulin and amyloid β, and has been linked to type 2 diabetes mellitus and Alzheimer's disease. We examined the thiol sensitivity of IDE using S-nitrosoglutathione, reduced glutathione, and oxidized glutathione to distinguish the effects of nitric oxide from that of the redox state. The in vitro activity of IDE was stud...

A fiber coating from polyaniline (PANI) was electrochemically prepared and employed for Solid phase micreoextraction (SPME). The PANI film was directly electrodeposited on the platinum wire surface using cyclic voltametry (CV) technique. The same method was applied for the preparation of SPME fiber coated by polyaniline multiwalled carbon nanotubes (PANI/MWCNTs) composite. The concentration of ...

sub chronic exposure to lead in rats slows gastric emptying, but little is known about the effects of lead on gastric secretion. this study was designed to investigate the effects of lead on gastric acid secretion and its possible mechanisms in rats. lead acetate was dissolved in drinking water in a concentration of 1%. sodium acetate-containing water with a molar concentration similar to lead ...

nitration of potassium sulphamate was carried out using a mixture of sulphuric and nitric acid at -30 °c. the reaction time was optimized at the mole ratio of sulphuric to nitric acid of (1:3.5). the difference in product yield by changing the potassium to ammonium sulphamate was studied throughly. it was found that both the yield and purity of the product is better starting with potassium sulp...