AIM To investigate extent and nature of visual pathways involvement in children with clinically isolated syndrome (CIS). METHODS Forty-seven patients (age 11-17y) with CIS, which later proved to be multiple sclerosis (MS) onset, and 30 controls underwent visual evoked potentials (VEP) investigation within 12d from the appearance of the first signs of disease. Latency and amplitude of P100 pea...

The purpose of this study was to investigate the effects of refractive error on canine visual evoked potentials with pattern stimulation (P-VEP). Six normal beagle dogs were used. The refractive power of the recorded eyes was measured by skiascopy. The refractive power was corrected to -4 diopters (D) to +2 D using contact lens. P-VEP was recorded at each refractive power. The stimulus pattern ...

Effects of enflurane on visual evoked potentials (VEP) were studied in eight healthy female patients. Control VEP were recorded from the occipital electrode (OZ-CZ), and prominent negative (N70) and positive (P100) peaks were observed following flash light stimulation. After induction of anaesthesia with thiopentone, VEP were recorded at expired concentrations of 1.2, 1.8, 2.4 and 2.7% of enflu...

Trans-Resveratrol (RV) was encapsulated in multi-lamellar liposomes (MLLs) composed of a mixture phosphatidylcholine (P100), Tween 80 (T80) and water. The P100-to-T80 ratio as well their water content were chosen based on previous study to promote transdermal transport RV. effect RV the size, elasticity, charge MLLs evaluated encapsulation apparent solubility diffusion artificial skin, namely S...

INTRODUCTION Emotional stimulus is processed automatically in a bottom-up way or can be processed voluntarily in a top-down way. Imaging studies have indicated that bottom-up and top-down processing are mediated through different neural systems. However, temporal differentiation of top-down versus bottom-up processing of facial emotional expressions has remained to be clarified. The present stu...

The intersubject and intrasubject reproducibility of the VEP was evaluated using two different methods of producing pattern reversal--a mirror/projector system and a light-emitting diode (LED) system. Intersubject reproducibility was determined in 100 normal subjects (50 males, 50 females). Ten subjects were studied on ten different occasions over 11 months to establish intrasubject reproducibi...

Signal transducer and activator of transcription 6 (STAT6) is a regulator of transcription for interleukin-4 (IL-4)-induced genes. The ability of STAT6 to activate transcription depends on functional interaction with other transcription factors and coactivators. We have characterized the mechanism of STAT6-mediated transcriptional activation by identifying STAT6 transcription activation domain ...

The life cycle transformation of the protozoan parasite Leishmania from promastigote to amastigote is accompanied by changes in the level of expression of a number of proteins whose function may be necessary for parasite survival in the sandfly vector or mammalian host. To genetically characterize these proteins, we have cloned and characterized cDNA sequences that vary in abundance during the ...

BACKGROUND This study aimed to explore the characteristics of event-related potentials induced by facial emotion recognition in patients with first-episode schizophrenia and in their siblings. METHODS In this case-control study, 30 first-episode schizophrenia patients, 26 siblings, and 30 healthy controls were enrolled. They completed facial emotion recognition tasks from the Ekman Standard F...

The processing of emotional faces and bodies has been associated with brain regions related to empathic responding in interpersonal contexts. The aim of the present Electroencephalography (EEG) study was to investigate differences in the time course underlying the processing of bodies and faces showing neutral, happy, or angry expressions. The P100 and N170 were analyzed in response to the pres...