نتایج جستجو برای: p53 and pcna
تعداد نتایج: 16836719 فیلتر نتایج به سال:
افزایش چشمگیر بکارگیری امواج مایکروویو بویژه در تبادل اطلاعات، از جمله ارتباطات شخصی، عمومی، نظامی و پزشکی، ما را بر آن داشت که به تحقیقاتی پیرامون آثار بیولوژیکی این نوع امواج بپردازیم. در این تحقیق، سلول لاین کلیه میمون سبز آفریقایی را در حالات مختلف استراحت و رشد تحت تأثیر امواج مایکروویو با توان ثابت در زمانهای مختلف قرار دادیم و آسیب سلولی و رشد سلولی را قبل و بعد از پرتودهی به دقت بررس...
Immunostaining for bcl-2 protein was performed in 27 colorectal adenomas and 108 colorectal adenocarcinomas. The aim of the study was to determine bcl-2 expression in correlation with p53, mdm-2 and Rb expression, with proliferation indices (Ki-67-LI, PCNA-LI) as well as with conventional clinicopathological variables. A higher proportion of adenomas (30.8%) than carcinomas (16.7%) expressed bc...
BACKGROUND Alveolar echinococcosis (AE) is characterized by the tumor-like growth of Echinococcus (E.) multilocularis. Very little is known on the influence of helminth parasites which develop in the liver on the proliferation/growth arrest metabolic pathways in the hepatocytes of the infected liver over the various stages of infection. METHODOLOGY/PRINCIPAL FINDINGS Using Western blot analys...
It has been proposed that diverse anticancer drugs and radiation therapy may induce a mode of cell death with the characteristics of apoptosis. Since apoptosis is under the control of several oncogenes, we analyzed the expression of the protein encoded by the proto-oncogenes bcl-2 and p53. Furthermore, we studied cell proliferation [using PC-10 mAb to proliferating cell nuclear antigen (PCNA)] ...
BACKGROUND Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely related with the cell cycle G2/M phase regulation. The present study aimed to analyze the relationship between CDK1 and the proliferation and apoptosis of ovarian cancer cells, invest...
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