Paget-Schroetter syndrome is thrombosis of the subclavian or axillary vein due to repetitive use of the upper limbs. We present a case of PagetSchroetter syndrome in a man who regularly performed weightlifting as part of his routine workout at the gymnasium. The mechanisms of the disease and its treatment are discussed. This diagnosis should be considered in unexplained subclavian or axillary v...

Four cases of Paget disease of the skull were studied with magnetic resonance (MR) imaging. With optimal use of projection and technical factors, MR permits simultaneous demonstration of osseous deformity and its relation to the underlying soft tissues. Effects on the brain caused by thickened calvaria and brainstem compression from basilar impression can be detected readily on a single sagitta...

A 41-year-old white female patient with complaints of lumbar pain for more than three years, without irradiation, underwent several radiological examinations. Her condition was diagnosed by means of biopsy, as monostotic Paget' s disease in the third lumbar vertebra. This is an uncommon location.

Hospital King’s Lynn NHS Foundation Trust, King’s Lynn, UK. James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK. Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough, UK. West Suffolk Hospitals NHS Foundation Trust, Bury St Edmunds, UK. Mid Essex Hospital Services NHS Trust, Chelmsford, UK. MRC Biostatistics Unit, Institute of Public Health, University of...

The simian figure of the country gentleman from the north of England, who was Sir James Paget's first reported case (1877) of osteitis deformans, hobbles still through all accounts of this disease: he exemplifies most of the known complications. Paget himself learnt little more from the twenty-two other cases he saw (1882, 1889), and since then a forest of at least 700 articles, covering over 2...

BACKGROUND Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an ...

The patient was a 91-year-old man with change in nipple appearance, itching and redness, and a palpable breast mass. At presentation, mammary Paget's disease (PD) was clinically suspected. Skin biopsy was performed and showed epidermis invaded by Paget cells, characterized by hyperchromatic nuclei and abundant pale-staining cytoplasm. Computed tomography and mammary ultrasonography confirmed th...

Giving cytomegalovirus (CMV) prophylaxis to CMV positive recipients is expensive in a resource-limited setting like South Africa. We report a retrospective analysis of CMV disease in 47 CMV donor/recipient positive (D+/R+) adult renal transplant patients (> 80% African Blacks) from February 2000 to November 2004 who had received four drug induction immune suppression. We commenced routine valga...

INTRODUCTION Giant cell tumor of the bone is a relatively uncommon tumor. It is characterized by the presence of multinucleated giant cells. The tumor is usually regarded as benign. In most patients, giant cell tumors have an indolent course, but tumors recur locally in as many as 50% of cases. Metastasis to the lungs may occur. Cooper first reported giant cell tumors in the 18th century. In 19...