BACKGROUND Irreversible electroporation (IRE) with needle electrodes is being explored as treatment option in locally advanced pancreatic cancer. Several studies have shown promising results with IRE needles, positioned around the tumor to achieve tumor ablation. Disadvantages are the technical difficulties for needle placement, the time needed to achieve tumor ablation, the risk of needle trac...

Solid pseudopapillary tumors of the pancreas (SPT) are rare tumors of the pancreas with low malignancy potential and a very good prognostic outcome after surgery. The outcome after radical resection is favourable. A case of solid-pseudopapillary tumor (SPT) of the pancreas in a 20-year-old woman is presented. The patient underwent resection of the mass in the pancreatic head and pancreaticoduod...

AIMS/HYPOTHESIS Sirtuin 1 (Sirt1) has been reported to be a critical positive regulator of glucose-stimulated insulin secretion in pancreatic beta-cells. The effects on islet cells and blood glucose levels when Sirt1 is deleted specifically in the pancreas are still unclear. METHODS This study examined islet glucose responsiveness, blood glucose levels, pancreatic islet histology and gene exp...

BACKGROUND In human acute pancreatitis two different types of secretory phospholipase A2 (PLA2) have been found. AIM To analyse the specific pattern of distribution of these PLA2 activities and their pathophysiological role in experimental acute pancreatitis. SUBJECTS AND METHODS Catalytic activities of secretory type I (pancreatic) and type II (non-pancreatic) PLA2 and the protein concentr...

background: oral vanadyl sulfate (vanadium) induces normoglycemia, proliferates beta cells and prevents pancreatic islet atrophy in streptozotocin-induced diabetic rats. soteriological method is used to quantitate the proliferative effects of vanadium on beta-cell numbers and islet volumes of normal and diabetic rats. methods: adult male sprague-dawley rats were made diabetic with intravenous s...

heterotopic pancreas is an uncommon developmental anomaly of upper gastrointestinal tract. heterotopic pancreas tissue is very rarely found in ileum. intussusception in children is usually idiopathic, but definitive aetiology can be established in 90% of adult cases. we are reporting a case of pancreatic heterotopia presenting as a lead point of ileo-ileal intussusception in a 1year 3month year...

Extracorporeal high-intensity focused ultrasound (HIFU) can be used to ablate tissue noninvasively by delivering focused ultrasound energy from an external source. HIFU for clinical treatment of pancreatic cancer has been reported; however, systematic evaluation of the safety and efficacy of pancreatic ablation with HIFU has not been performed. The objectives of this in vivo study are as follow...

BACKGROUND Insulinomas are a rare cause of hyperinsulinaemic hypoglycaemia (HH) in children. The clinical features, investigations, management and histology of these rare pancreatic tumours in children have not been described in a large cohort of patients. METHODS We conducted a retrospective review of cases diagnosed between 2000 and 2012, presenting to two referral centres in the United Kin...

Abstract Background Snake bite is a major public health problem, especially in the tropical areas of world, which World Health Organization aims to eradicate. According National Crime Records Bureau India, where agriculture mainstay employment attributes about 8660 mortalities year. Histopathological results are immense help establishing cause death those snake cases other circumstantial shreds...