purpose: to evaluate demographics and therapeutic outcomes of patients with third nerve palsy who had been treated between 1999 to 2009 at labbafinejad medical center. methods: in this retrospective study, we evaluated 52 patients with third nerve palsy who had been referred to labbafinejad medical center over a ten-year period. results: in this retrospective study, subjects who had been treate...

Dear Editor, Myotonia congenita (MC) is a group of genetically and clinically heterogeneous congenital neuromuscular channelopathies characterized by the delayed relaxation of the muscles after voluntary contraction, stiffness, hypertrophy, transient weakness, and cramping. MC is mostly associated with dominant or recessive mutations in CLCN1. However, SCN4A mutations are occasionally implicate...

Acute hypokalemic paralysis is a rare cause of acute weakness. Morbidity and mortality associated with unrecognized disease can occur and include respiratory failure and possibly death. Common causes of hypokalemic paralysis include thyrotoxic periodic paralysis (TPP) which is a disorder most frequently seen in Asian males. TPP is characterized by sudden onset of hypokalemia and paralysis that ...

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THOMSEN'S disease (myotonia congenita), dystrophia myotonica (myotonia atrophica), and paramyotonia are characterized by the presence of myotonia. As an isolated symptom, myotonia had already been described by Benedikt (1874) and Leyden (1874) when Thomsen (1876) published his paper (following the refusal by the Prussian army medical officers of a certificate of the disease in one of his sons),...

INTRODUCTION Distinguishing conversion disorder from malingering presents a significant challenge as the diagnosis ultimately depends on the patient's subjective report and the clinician's suspicion of an intention to deceive. Using hypnosis to manipulate the intentionality of movement inhibition in the same subjects, we used positron emission tomography (PET) to determine whether failure to mo...

Thyrotoxic periodic paralysis is a unique disorder that causes episodic proximal lower extremity muscle weakness in patient who already has hyperthyroid state and not treated for the underlying disease state. The affected population mostly includes Asian origin specifically male gender (vs most thyroid affects women gender). Precipitating factors include addition to are strenuous exertion, high...