The parathyroid gland secretes parathyroid hormone (PTH) which is a key element in the regulation of serum calcium. The PTH elevates serum calcium activities by regulating its action on the bones, kidneys and small intestine. The set point of PTH secretion defines the sensitivity of the parathyroid glands to calcium concentration. Secondary hyperparathyroidism (SHPT) is a common complication of...

In the last decade, there has been a rapid refinement in ultrasound technology and especially the development of high resolution ultrasound has led to an imperative part for ultrasound in the assessment of the thyroid and parathyroid disorders. Ultrasound images play a major role in the management of thyroid disorder and, in precise, in the management of recurring neck complications after thyro...

INTRODUCTION Secondary hyperparathyroidism (2HPT) is a common complication in uraemic patients. When medical therapy, including high doses of intravenous calcitriol, fails to suppress the pathological secretion of parathyroid hormone (PTH), one of the newly developed interventional techniques, such as percutaneous ethanol injection therapy (PEIT), is an option before taking the surgical solutio...

Primary hyperparathyroidism is a generalized disorder of bone and mineral metabolism caused by autonomous secretion of parathyroid hormone. It is primarily seen in adults with typical age of presentation between third and fifth decades of life. Juvenile hyperparathyroidism is a rare disorder. The common presentations in order of incidence are fatigue and lethargy, headache, nephrolithiasis, nau...

The hypercalcemia of hyperparathyroidism (HPT) can cause devastating effects to the patient and only surgical removal of the hyperfunctioning parathyroid tissue can definitely cure the disease. Radionuclide parathyroid imaging has no role in the diagnosis of hyperparathyroidism or in the selection of the type of treatment. However, once surgery is decided (99m)Tc-sestamibi scanning can localize...

OBJECTIVES To describe atypical ultrasound features of parathyroid lesions and correlate them with clinical presentation and histopathology. MATERIALS AND METHODS Retrospective review of 264 patients with primary hyperparathyroidism who underwent ultrasound imaging prior to parathyroidectomy was performed. Patients with atypical ultrasound findings (n = 26) were identified; imaging findings w...

Received 10/30/2002; revised 11/19/2002; accepted 12/16/2002. For correspondence or reprints contact: Hatice Uslu, M.D., Department of Nuclear Medicine, Medical School, Atatürk Universty, 25240 Erzurum, Turkey. Tel: 90-442-236-09-00, Fax: 90-442-236-08-84, E-mail: [email protected] Backgrounds: Tl/Tc-pertechnetate subtraction scintigraphy is recognized as a useful procedure in the preoperat...

Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia in outpatients. It is more common in females, after menopause, and the prevalence is 1 to 4:1000 in the general population. Patients with PHPT have abnormal regulation of PTH secretion, resulting in elevated serum calcium and inappropriately high or normal PTH in relation to the calcium value. Sporadic PTH-secreting ad...

AIM Minimally invasive resection of hyperfunctional parathyroid glands is an alternative to open surgery. However, it requires a precise preoperative localization. This study evaluated the diagnostic use of magnetic resonance (MR) imaging, parathyroid scintigraphy, and consecutive image fusion. PATIENTS, METHODS 17 patients (9 women, 8 men; age: 29-72 years; mean: 51.2 years) with primary hyp...