BACKGROUND Dizziness is a frequent complaint of patients with Parkinson's disease (PD), and orthostatic hypotension (OH) is often thought to be the cause. We studied whether benign paroxysmal positional vertigo (BPPV) could also be an explanation. AIM To assess the prevalence of benign paroxysmal positional vertigo in patients with Parkinson's disease, with and without dizziness. METHODS 30...

CONTACT US 1. http://www.parkinsons.org.uk/content/what-parkinsons. Accessed August 2015. 2. Cancela J, Arredondo MT, Hurtado O. Guidelines for the economic analysis of a telemetic platform for Parkinson's disease monitoring. BIBE. 2013: page 1-4. IEEE. 3. Wood et al. Incidence and predication of falls in Parkinson's disease: a prospective multidisciplinary study. J Neurol Neurosurg Psychiatry....

BACKGROUND While the cause of Parkinson's disease (PD) remains unknown, evidence suggests certain environmental factors, such as well water drinking, herbicides, pesticides exposure and neurotoxins, may trigger the chain of oxidative reactions culminating in the death of dopaminergic neurons in substantia nigra to cause Parkinsonism. To investigate the possible impact of environmental risk fact...

OBJECTIVE Reduced verbal fluency (VF) has been reported in patients with Parkinson's disease (PD), especially those treated by Deep Brain Stimulation of the subthalamic nucleus (STN DBS). To delineate the nature of this dysfunction we aimed at identifying the particular VF-related operations modified by STN DBS. METHOD Eleven PD patients performed VF tasks in their STN DBS ON and OFF conditio...

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical databases. In this study, we divided 11 data mining algorithms into five groups which are applied to a dataset of patient’s clinical variables data with Par...

The aim of the study was to investigate the efficacy of homemade tolcapone in treatment of patients with Parkinson's disease (PD). Eighty patients with PD were subjected to randomized, double-blind, placebo-controlled and parallel-group study. PD patients were randomly divided into the tolcapone treatment group (41 cases) and placebo group (39 cases). Each patient received 1 pill of tolcapone o...

Background: Experimental evidence supports a preventative role for non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson’s disease (PD). Methods: We investigated associations between use of aspirin, nonaspirin NSAIDs, and acetaminophen and PD in a large population-based casecontrol study using Danish health and pharmacy registries. We identified 1,931 PD cases reported in hospital or outp...

Research derived from non-invasive brain imaging modalities has been used to explore the spatial and temporal organization of the neural systems supporting human behavior and causing brain disorders. Imaging modalities of interest include positron emission tomography, event-related potentials, electro-and magnetoencephalography, and magnetic resonance imaging (MRI). In this talk, we will presen...

Parkinson's disease (PD) is a progressive neurodegenerative disorder resulting in part from loss of nigrostriatal dopamine (DA) neurons. Treatments act only to relieve symptoms. It is therefore essential to develop treatments that slow or reverse the neurodegenerative process. Here, I explored exercise as a potential treatment against a 6-hydroxydopamine (6-OHDA) rat model. 6-OHDA causes select...