BACKGROUND The exploitation of the surface display system of food and commensal lactic acid bacteria (LAB) for bacterial, viral, or protozoan antigen delivery has received strong interest recently. The Generally Regarded as Safe (GRAS) status of the Lactococcus lactis coupled with a non-recombinant strategy of in-trans surface display, provide a safe platform for therapeutic drug and vaccine de...

The spontaneous healing of aqueous pores in poly(D,L-lactic-co-glycolic acid) (PLGA) drug delivery systems has been identified to play a key role in terminating the burst release of large molecules, and to provide a means for novel aqueous-based microencapsulation. To examine healing of PLGA, pores were created of defined size and depth on the surface of thin PLGA films by stamping with blunt-t...

OBJECTIVE During surface cooling with ice-cold water, safety and effectiveness of transthoracic defibrillation was assessed. METHODS In a pig ventricular fibrillation cardiac arrest model, once (n = 6), defibrillation was done first in a dry and then in a wet condition using the ThermoSuit System (Life Recovery Systems, HD, LLC, Kinnelon, NJ), which circulates a thin layer of ice-cold water (...

The objective of this study is to obtain quantitative evidence of pore-scale immiscible fluid distribution in oil-wet and water-wet porous media using X-ray computed microtomography. Temporal and spatial saturation profiles, as well as surface and interfacial areas, are thoroughly analyzed through cycles of drainage and imbibition using samples with different wetting characteristics but similar...

OBJECTIVES To evaluate the shear bond strength and site of failure of brackets bonded to dry and wet enamel. STUDY DESIGN 50 teeth were divided into ten groups of 5 teeth each (10 surfaces). In half the groups enamel was kept dry before bonding, and in the other half distilled water was applied to wet the surface after etching. The following groups were established: 1) Acid/Transbond-XT (dry/...

in many urban areas, groundwater has been exploited neglecting to wet and dry periods owing to of surface water deficit. in this study, using the percent of normal rainfall index, 36 year (1971-2008) were studied and a drought event and a wet event were determined. the reason to choose two consecutive years is the effect of early wet period on groundwater quality. physicochemical characteristic...

This paper presents an experimental investigation into the mechanisms altering pull-out behaviour of partially pulled hooked-end steel fibres inside artificial crack exposed to wet–dry cycles chlorides and carbon dioxide for 6 months. Mechanical corrosion damage at surface fibre was investigated using three-dimensional optical interferometric profiling, petrographic analyses were used describe ...

Abstract While the relationships between dry land surface conditions, heat, and aridity have been well‐established, few studies addressed whether global warming will affect ability of wet conditions to moderate high temperatures atmospheric aridity. Using Coupled Model Intercomparison Project Phase 6 models, we demonstrate that absolute changes in monthly maximum temperature distribution during...

Does the dryness of tooth surface influence the bonding efficacy of self-adhesive resin cement? I would like to know how much I should dry the tooth surface for better adhesion of self-adhesive resin cement. Q Self-adhesive resin cements are designed to adhere to the tooth substrate without a separate adhesive or etchant. The first commercial product, RelyX Unicem, was launched in 2002 and gain...