Pathological laughter is an uncommon symptom usually caused by bilateral, diffuse cerebral lesions. It has rarely been reported in association with isolated cerebral lesions. Midbrain involvement causing pathological laughter is extremely unusual. We describe three patients who developed pathological laughter after midbrain and pontine-midbrain infarction. In two patients a small infarction in ...

Exposure therapy for anxiety disorders has been one of success stories of clinical psychology and psychiatry. Nevertheless, a significant minority of patients fail to benefit from extant treatments. This clinical impasse is prompting renewed attempts to understand fear and its reduction at neural, cellular, and molecular as well as behavioral levels of analysis. The purpose of this article is t...

With the introduction of Cullen’s calorimetric method (1) of estimating the hydrogen ion concentration of blood serum or plasma, it seemed possible for every laboratoryto have a methodemploying minimum material and apparatus and yet secure reliable results. It is generally conceded that the results obtained by the method on normal human plasma or serum agree very well with the true pH as determ...

This paper deals with one-dimensional (1D) nonlinear Schrödinger equation with a multiplicative potential, subject to Dirichlet boundary conditions. It is proved that for each prescribed integer b > 1, the equation admits smallamplitude quasi-periodic solutions, whose b-dimensional frequencies are small dilation of a given Diophantine vector. The proof is based on a modified infinitedimensional...

Objective: This article reports the initial validation of an instrument designed to measure problem gambling on video gambling devices. Methods: Two samples were collected and included: • individuals at random lists of playing locations for all counties in one state (n = 553) • a general public sample also drawn from each county (n = 542). Results: The scales attained high levels of internal co...