Developmental coordination disorder (DCD) is a recognized childhood disorder mostly characterized by motor coordination difficulties. Joint hypermobility syndrome, alternatively termed Ehlers-Danlos syndrome, hypermobility type (JHS/EDS-HT), is a hereditary connective tissue disorder mainly featuring generalized joint hypermobility (gJHM), musculoskeletal pain, and minor skin features. Although...

This study empirically evaluates the psychometric properties of a new mother-answered developmental instrument for toddlers, the Toddler Language and Motor Questionnaire (TLMQ). Mothers of 1132 15- to 38-month-old children filled out a 144-item instrument, tapping the toddlers' competences in five language and motor subtests. Concurrent validity was investigated in an independent sample by admi...

We previously reported that foetal valproate exposure impairs intelligence quotient. In this follow-up investigation, we examined dose-related effects of foetal antiepileptic drug exposure on verbal and non-verbal cognitive measures. This investigation is an ongoing prospective observational multi-centre study in the USA and UK, which has enrolled pregnant females with epilepsy on monotherapy f...

OBJECTIVE This study aimed to determine the impact of a ketogenic diet (KD) on neurobehavioral development when used to treat children with intractable epilepsy, confirming the efficacy of the KD, as well as the correlation between early electroencephalography (EEG) changes in the early stage with treatment efficacy. METHODS We enrolled 42 children who were starting treatment for intractable ...

Most of the developmental instruments that measure cognitive development in children rely heavily on fine motor skills, especially for young children whose language skills are not yet well developed. This is problematic when evaluating the cognitive development of young children with motor impairment. The purpose of this study is to assess the need for a Low Motor adapation of a standardized in...

OBJECTIVE The role of familial, demographic, developmental, and treatment-mediating factors on treatment outcome of sexually abused preschool children was evaluated 6 and 12 months after treatment. METHOD Forty-three sexually abused preschool children and their parents who were evaluated shortly after disclosure of sexual abuse and then were provided with one of two treatment interventions we...

BACKGROUND The Bayley Scales of Infant and Toddler Development (III) is a tool developed in a Western setting. AIM To evaluate the development of a group of inner city children in South Africa with no neonatal risk factors using the Bayley Scales of Infant and Toddler Development (III), to determine an appropriate cut-off to define developmental delay, and to establish variation in scores don...

BACKGROUND Children with congenital heart disease are at risk for developmental delay. This study sought to identify early risk factors for abnormal developmental trajectories in children with congenital heart disease. METHODS AND RESULTS Children with congenital heart disease at high risk for developmental delay, without known genetic abnormality, and with ≥3 assessments by the use of the Ba...

objective neuropsychological impairment is an important co-morbidity of chronic epilepsy. the aim of this study was to determine the state of the cognitive and motor development of patients with refractory epilepsy. materials & methods  we studied 150 consecutive children with epilepsy who were referred to mofid children hospital, a third level public referral university hospital in tehran, ira...

background unlike developed countries, data from the developing world regarding motor developmental disorders is scarce. objectives in the present study, we used the infant neurological international battery (infanib) test to determine the prevalence of motor impairment in 4-18 month-old infants in alborz province, iran, in 2010. patients and methods this study was a descriptive-analytic study ...